37 citations,
January 2016 in “Australasian Journal of Dermatology” Scalp melanomas are more dangerous and often missed, needing earlier detection.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
67 citations,
August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
January 2008 in “Linchuang pifuke zazhi” Betamethasone activates and increases the growth of certain skin cells from hair follicles.
2 citations,
June 2013 in “In Vitro Cellular & Developmental Biology - Animal” Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
2 citations,
May 2018 in “Australasian Journal of Dermatology” Some patients' hair grew back black and white after chemotherapy.
January 2006 in “Chinese Journal of Dermatology” Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
January 2003 in “Linchuang pifuke zazhi” Melanin granules can be expelled by exocytosis.
8 citations,
June 2016 in “Journal of Cutaneous Pathology” Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
June 2023 in “JAAD Case Reports” A man had a rare skin cancer that looked like a bald spot.
September 2022 in “Journal of Sulaimani Medical College” The combination treatment showed some improvement but wasn't significantly better than using betamethasone valerate alone.
15 citations,
April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
March 2018 in “John Wiley & Sons, Ltd eBooks” Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.
August 2018 in “Journal of the American Academy of Dermatology” Calcipotriol may effectively treat hair loss in alopecia areata, working better in children than adults.
7 citations,
May 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” White hair follicles in vitiligo have fewer and less functional melanocytes.
84 citations,
April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
39 citations,
December 2008 in “Clinics in Dermatology” Dermoscopy has improved skin cancer diagnosis and has expanding applications in dermatology, but requires staying updated with new research and techniques.
6 citations,
November 2017 in “Journal of the European Academy of Dermatology and Venereology” A woman got melanoma on her scalp after anti-hair loss treatment with injections.
15 citations,
July 1999 in “Dermatologic Clinics” The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
13 citations,
March 2020 in “Frontiers in cell and developmental biology” A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
56 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
May 2009 in “The American Journal of Dermatopathology” Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
5 citations,
September 2002 in “Archives of Dermatology” Dermatologists diagnose and manage melanoma more effectively than general practitioners.
Hair turning darker can be a sign of skin cancer.
March 2009 in “Chinese Journal of Dermatology” Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
Surgical repigmentation can permanently restore color to white hair in vitiligo patients.
3 citations,
October 1982 in “Postgraduate Medicine” Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.
4 citations,
January 2019 in “Micron” Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.