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RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Solanum nigrum may help treat hair loss.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.