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Early balding in men might be a male hormonal equivalent of polycystic ovaries syndrome in women.

Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.

Cells that move well may improve hair loss treatments by entering hair follicles.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

The YH complex, made from certain plant extracts, effectively promotes hair regrowth and could be a potential treatment for hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

EVAL membranes help create cell structures that can regrow hair follicles.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Alpha Lipoic Acid helps protect skin from smoking damage.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Eclipta alba extract could be a promising natural treatment for hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Four-amino acid part makes enzyme sensitive to finasteride.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.