The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.
87 citations,
March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
16 citations,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
11 citations,
August 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
6 citations,
November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
5 citations,
February 2021 in “Gels” HYDRO DELUXE BIO hyaluronic acid hydrogel is compatible with skin cells, may reduce inflammation, promote blood vessel growth, and protect against oxidative stress, suggesting it could help revitalize hair follicles.
4 citations,
December 2017 in “PubMed” Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.
2 citations,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
January 2024 in “Molecules (Basel. Online)” Juglone from walnut extracts may help repair damaged hair.
The research developed a human hair keratin and silver ion hydrogel that could help heal wounds.
December 2022 in “Molecular Pharmaceutics” Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
December 2022 in “Scientific Reports” Compound 4 is a promising treatment for hair loss with low toxicity.
186 citations,
February 2013 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
92 citations,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
45 citations,
December 2007 in “The FASEB journal” There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
44 citations,
January 2004 in “American journal of clinical dermatology” Understanding genetic mutations helps diagnose and treat skin disorders like ichthyosis.
35 citations,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
27 citations,
November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
22 citations,
August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
19 citations,
March 2016 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
15 citations,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
9 citations,
May 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
8 citations,
July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
8 citations,
September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
5 citations,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
2 citations,
January 2022 in “Materials today: proceedings” Caffeine may be good for hair growth and skin care because it binds well with keratin.