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Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride doesn't affect erections much, but may decrease libido in men.

Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Finasteride does not negatively affect male reproductive function.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Eclipta alba extract could be a promising natural treatment for hair loss.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Compound 15a was effective in inhibiting 5α-reductase.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.

Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.