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MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Rice bran extract might help prevent hair loss.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

β-sitosterol and brassicasterol may help treat hair loss.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.