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Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Quercetin may help with PCOS symptoms, but more research is needed.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Claudin-1 is important for the barrier function and growth of hair.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.