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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Finasteride doesn't affect hormone levels in normal men.

Rats had lasting erectile problems after stopping a certain medication.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

No link found between specific genes and female pattern hair loss.

Stopping alpha-blocker medication after 6-9 months is safe and effective for most patients with bladder outlet obstruction.

Finasteride reduces movement issues in Parkinson's disease rats.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Finasteride doesn't affect erections much, but may decrease libido in men.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Certain drugs change freshwater snail shells to a "banana" shape.

Women with more 3α,17β-androstanediol glucuronide compared to sex hormone binding globulin are more likely to have female pattern baldness.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Older age, pre-existing skin conditions, cirrhosis, and pegylated interferon use increase the risk of skin issues during hepatitis C treatment.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.