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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Understanding the mouse hair cycle is crucial for cancer research.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Human hair follicles can regenerate after removal, but with low success rate.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Inactive hair follicle stem cells help prevent skin cancer.