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This study demonstrated that benzothiazepines, such as diltiazem and JTV-519, exert anxiolytic-like effects through allopregnanolone biosynthesis in mice, similar to carbamazepine.

This review suggests that GABAergic neuroactive steroids modulated by alcohol could play a role in vulnerability to alcohol use disorders, providing a rationale for further therapeutic exploration.

This study found that while dutasteride significantly altered pregnane metabolism in mares during late gestation, it did not impact pregnancy outcomes, highlighting the complexity of pregnane metabolism and the necessity of LC-MS/MS for accurate measurement.

This article reviews the role of androgens in male pattern hair loss and its emotional impact, but reports no new clinical findings.

This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.

This study suggests that while treatments like allopregnanolone, trazodone, antipsychotic drugs, and hormonal therapies may offer potential benefits for post-finasteride syndrome, further research is necessary to validate their effectiveness.

This source highlights potential treatments for post-finasteride syndrome, including allopregnanolone, trazodone, antipsychotic drugs, and hormonal therapies, but notes further research is necessary to confirm their efficacy.

This study found that, although finasteride reduced dihydrotestosterone levels in males with heavy episodic drinking, it did not significantly alter brain activation or craving but was linked to a stronger desire not to drink.

This review paper explores hair physiology, the pathophysiology of alopecia areata, and evaluates the potential of herbal plants in treating alopecia areata compared to allopathic methods. Results are not reported in this source.

This review explores the physiology of hair, the pathophysiology of alopecia areata, and the potential of herbal treatments compared to conventional allopathic methods for managing this autoimmune condition. Results are not reported.

This article explores the pathophysiology of alopecia and reviews various treatment options, including allopathic, homeopathic, naturopathic, cosmeceutical, and ayurvedic approaches, in light of the increasing interest in hair health and the rise in alopecia cases. Results are not reported.

This article explores the various causes of alopecia and provides an overview of treatments such as allopathic, homeopathic, naturopathic, cosmeceutical, and ayurvedic methods, emphasizing recent advancements in addressing hair loss.

This review article concluded that certain herbal remedies targeting 5-alpha reductase inhibitors may prevent hair loss in androgenetic alopecia by blocking dihydrotestosterone production, although standardizing the concentration of active herbal compounds remains a challenge.

In this study on sheep, researchers found that 10% Aloe vera extract had satisfactory healing effects on skin wounds, demonstrating effective macroscopic and partially differing microscopic results compared to control groups after 22 days of treatment.

This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.

This case report describes a middle-aged man with chronic tophaceous gout who experienced a rare form of non-scarring alopecia due to urate crystal deposition around hair follicles, leading to hair loss that remarkably improved with targeted treatment including allopurinol and lifestyle changes.

This study examined lipid changes in rat models of polycystic ovarian syndrome, finding that letrozole and dihydrotestosterone treatments led to some lipid alterations similar to human PCOS, while other changes were unique to the models.

In this case, ayurvedic medicines were reported to effectively manage a patient with alopecia areata, with fewer side effects and reduced relapse rates compared to conventional treatments.

In this animal study, agmatine exhibited a protective effect against seizures related to hormone fluctuations, with results suggesting that its anticonvulsant properties may involve interactions with central neurosteroids in female rats experiencing progesterone withdrawal.

This review article reports that many herbal drugs show potential for treating alopecia effectively and with fewer side effects compared to synthetic drugs, addressing a common issue among urban residents due to stress and environmental factors.

In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.

In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.

This study found that neurosteroids influence oxytocin secretion in sheep, particularly during stress and pregnancy, suggesting their role in protecting and maintaining pregnancy under harmful conditions.

This review examines the physiology of skin flap necrosis and various substances studied to improve flap viability, noting that promising results are mostly from animal studies, with nitroglycerin already tested in humans.

This discussion concluded that many herbal home remedies are effective for treating alopecia and other hair conditions without causing adverse reactions, as opposed to allopathic medicines that often have undesirable side effects.

In this study of young adults in Angamaly, only 5% were found to have Polycystic Ovary Syndrome, with dietary choices playing an important role in symptom management.

This case report documents a 44-year-old female with Down's syndrome who was diagnosed with both rheumatoid arthritis and gouty arthritis, highlighting her specific clinical presentation and treatment regimen.

This study suggests that 5α-reductase-mediated metabolism of progesterone contributes to the differentiation of endometrial stromal cells, potentially influencing progesterone levels and promoting cell differentiation.

This study found that in animal models of Tourette syndrome, stress-induced tic-like behaviors and sensorimotor gating deficits were reduced by finasteride, suggesting a role for neurosteroids like allopregnanolone.

This study suggests that progesterone may have a complex role in absence epilepsy, facilitating seizures through conversion to allopregnanolone, but potentially reducing them during pregnancy.