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This article reviews the clinical signs, diagnostic approaches, and treatment options for hyperandrogenism in women, focusing on hirsutism and specifies that cyproterone acetate is effective for severe cases, but reports no new clinical results.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.

This review discusses the advancements in biologic skin substitutes for wound treatment and their potential in enhancing cutaneous regeneration but reports no new clinical results.

This study found that progesterone's antiseizure effects in mice occurred primarily through conversion to allopregnanolone, rather than through the progesterone receptor, as evidenced by results in PR knockout mice.

This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.

This study found that treatment with finasteride in fetal sheep reduced the protective neurosteroid allopregnanolone, leading to increased cell death in the hippocampus following induced fetal asphyxia.

This study found that midazolam, unlike clonazepam, increased neurosteroid levels and affected synaptic inhibition and plasticity in rat hippocampal neurons, suggesting unique actions via dual receptor activation.

This study found that progesterone protects rat Purkinje cells during oxygen-glucose deprivation by activating GABA A receptors through its metabolite, allopregnanolone.

Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.

This review explores the potential role of pregnane neurosteroids in modulating alcohol withdrawal symptoms, suggesting a therapeutic target for treating alcohol dependence, but reports no new clinical results.

This study found that inhibiting allopregnanolone synthesis in late gestation fetal sheep increased apoptosis and dead cell count in the hippocampus and cerebellum, effects that were mitigated by alfaxalone co-infusion.

This study found that decreased allopregnanolone levels through inhibition or intrauterine growth restriction in guinea pigs were linked to altered brain development markers, suggesting a role for neurosteroids in fetal brain protection and development.

This case study reported a 23-year-old woman with chronic myeloid leukemia who developed permanent hair loss after chemotherapy and did not respond to topical minoxidil treatment.

In this study, finasteride dose-dependently inhibited stress-induced increases in allopregnanolone in rats, while enhancing 20alpha-reduction of progesterone without affecting 3alpha-dihydroprogesterone or 11-deoxycorticosterone levels.

The researchers found that inhibiting soluble epoxide hydrolase, either genetically or pharmacologically, delayed the onset of chemically induced seizures related to GABA antagonism in experimental models.

In this study, withdrawal from progesterone and treatment with finasteride were associated with increased signs of depression-like behavior in female mice, suggesting decreased allopregnanolone levels may play a role.

This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

This study found that finasteride dose-dependently blocked the acquisition of ethanol drinking in mice and maintained reduced consumption even after treatment ended.

Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.

This study found that the anticonvulsant effects of progesterone against PTZ-induced seizures in mice require conversion to allopregnanolone, as shown by the reversal of these effects with a 5alpha-reductase inhibitor.

This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

This study found that progesterone can inhibit spinal reflex potentiation in ovariectomized rats through GABA(A) receptor activity, mediated by neurosteroid metabolism rather than direct progesterone receptor action.

This review focuses on neuroactive steroids' influence on GABA-ergic signaling and discusses challenges in developing them for various therapeutic uses, citing recent excitement from FDA approval of allopregnanolone for postpartum depression but reporting no new results.

This review discusses skin tissue engineering and highlights the potential role of microRNAs in improving bioengineered skin equivalents, concluding that further exploration of microRNA targets could address unmet clinical needs.

This article reviews treatment options for cutaneous T-cell lymphoma, including skin-directed therapies and aggressive treatments for advanced cases, but reports no new clinical results.

This study found that finasteride increased fetal arousal activity in late gestation sheep by suppressing pregnane steroid synthesis, suggesting reduced GABAA receptor-mediated inhibition.

This study suggests that both the central biosynthesis and metabolism of progesterone to 3α,5α‐THP in the ventral tegmental area are crucial for facilitating lordosis in female rats.