4 citations
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March 2005 in “Archives of Pathology & Laboratory Medicine” This case report describes a basal cell carcinoma arising in association with a vellus hair cyst, which the authors note has not been previously reported.
3 citations
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January 2011 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that variations in mouse skin thickness, influenced by gender and hair growth cycles, significantly affect optical scattering measurements, which are important for developing biomedical optics techniques.
1 citations
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January 2025 in “medRxiv” In this case-control study, researchers did not find genome-wide significant genetic variants for trichotillomania, but cases had higher polygenic risk for psychiatric disorders and certain neuropsychiatric-associated copy number variants.
1 citations
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January 2025 in “ARC Journal of Dermatology” This study suggests that among GLP-1 agonists, liraglutide and exenatide are linked to the highest rates of gastrointestinal issues, including potentially pancreatitis-related enzyme changes noted in animal models.
1 citations
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February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.
1 citations
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April 2018 in “Journal of Investigative Dermatology” This study found that topical simvastatin induced remission and hair regrowth in a mouse model of alopecia areata, potentially by modulating T cell activity and reducing pro-inflammatory cytokine signaling.
1 citations
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January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a mouse model to mimic PHGDH gene copy number gain, finding that increased PHGDH expression leads to abnormal melanin production, which may offer insights into its role in melanoma.
1 citations
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September 2013 in “Mayo Clinic Proceedings” This case study identified low iron stores, potentially linked to heavy menstrual periods, as a trigger for diffuse nonscarring alopecia in a 31-year-old woman, leading to a diagnosis of telogen effluvium, for which iron supplementation was prescribed.
This article provides a comprehensive guide on wig making, styling, and maintenance techniques but does not report any new research findings.
July 2026 in “Nature Communications” This study used spatial transcriptomics to investigate T cell-hair follicle interactions in cutaneous lupus erythematosus across mice, dogs, and humans, finding that CXCR3+ T cells and B cells are enriched in lesional skin, with implications for potential therapeutic targets.
This study observed that treating human hair with NaOH led to partially removed cuticles, resulting in better fiber cohesion and mechanical properties similar to wool, unlike bleach or formic acid treatments, which weakened the fibers.
February 2026 in “Macromolecular Bioscience” In this study, keratin‐based hydrogels incorporating calcium ions were developed to effectively deliver atorvastatin, showing potential for localized anti‐fibrotic therapy through controlled drug release and maintaining drug bioactivity in vitro, supported by thorough physicochemical and mechanical characterization.
September 2025 in “Journal of Dermatology Research and Therapy” In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.
In this case study, researchers reported the first documented instance of malignant transformation of congenital triangular alopecia into basal cell carcinoma in a 48-year-old woman, underscoring the importance of assessing long-standing alopecic areas for malignancy.
August 2025 in “Skin Appendage Disorders” This review highlights that while low-dose oral minoxidil appears well-tolerated in cancer patients post-chemotherapy, its use during active chemotherapy has shown potential benefits but remains under investigation, with preclinical studies suggesting a protective effect against chemotherapy-induced alopecia.
July 2025 in “Journal of Dermatology Research and Therapy” In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.
January 2025 in “Biomedicines” In this study, female rats given high doses of testosterone showed decreased endometrial thickness and lower mRNA levels of components in the LIF signalling pathway, indicating that excessive testosterone may negatively impact endometrial receptivity and potentially affect fertility.
September 2024 in “International Journal of Molecular Sciences” This study found that administering a supraphysiological dose of testosterone to female rats significantly reduced estrogen and progesterone levels, disrupted sex steroid receptor expression, and interfered with the embryonic implantation window, indicating potential implications for androgen-related endometrial conditions.
September 2024 in “Journal of the American Academy of Dermatology” This study observed that many individuals with alopecia areata seek or receive dietary and nutritional advice to manage their condition, often making changes such as taking supplements or adding specific foods, yet most reported no change in their disease status.
July 2024 in “Nursing Research” This study highlights the use of hair and fingernail cortisol levels as retrospective indicators of chronic stress, particularly in minoritized populations facing social stressors that increase the risk of mental health issues.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that hair with lower levels of keratin associated proteins reduced the foreign body response in mouse subcutaneous implant tests compared to hair with higher keratin levels.
March 2024 in “Journal of the American Academy of Dermatology” Taking medication for hair loss might cause sexual problems.
February 2024 in “Animals” This study observed that alopecia in rhesus macaques follows a seasonal pattern, with the highest hair loss in spring, and varies with reproductive state, as pregnant females experience the most significant alopecia and lowest hair regrowth, which resumes postpartum.
This study analyzed scalp hair proteins from healthy children and their mothers, finding that non-structural proteins could serve as promising biomarkers for understanding long-term developmental changes and health status linked to early childhood experiences.
October 2023 in “Journal of the Endocrine Society” This case report highlights that Sheehan's syndrome can still occur in developed countries due to factors like migration and delayed diagnosis, with diabetes insipidus sometimes masked by adrenal insufficiency.
August 2023 in “Journal of Investigative Dermatology” This study using scRNA-seq on 96 skin biopsies from 51 healthy individuals revealed distinct cell signaling pathways in different skin sites, including unique pathways in facial and palmoplantar skin, which may explain their varying susceptibilities to skin disorders.
April 2020 in “Online journal of complementary & alternative medicine” This article discusses the FDA approval of bremelanotide for premenopausal women with hypoactive sexual desire disorder and reports no clinical results.
April 2019 in “Journal of Investigative Dermatology” This study observed that simvastatin promoted hair regrowth in a mouse model of alopecia areata by reducing inflammatory markers and T cell proliferation, partly through disruption of isoprenoid metabolite production.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” This study found that increased PHGDH expression in mice led to earlier melanin and melanocyte presence in hair follicles but did not induce cancer.