95 citations
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June 2002 in “The Journal of Dermatology” In this study, using topical crude onion juice significantly improved hair regrowth in patients with patchy alopecia areata compared to tap water.
9 citations
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June 2022 in “Plants” This study found that shallot extract may promote hair growth in androgenetic alopecia by reducing inflammation and modulating gene expression related to key hair growth pathways.
8 citations
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August 2019 in “Journal of Drug Delivery and Therapeutics” This study aimed to formulate and evaluate a herbal gel containing Allium cepa extract for its physical properties, such as appearance, viscosity, and spreadability, but it does not report specific results or effectiveness in preventing hair loss.
3 citations
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October 2021 in “Journal of Cosmetic Dermatology” This study found that topical patches containing allicin from garlic extract may be a promising and cost-effective option for treating alopecia areata, offering better aesthetic acceptance than mashed garlic.
2 citations
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May 2023 in “Plants” In this study, Allium hookeri extract increased viability and size of dermal papilla cell spheroids and reduced oxidative stress effects, potentially promoting hair growth by regulating specific protein signaling pathways in human cells.
1 citations
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July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study investigates the potential of onion extract as a treatment for androgenetic alopecia by using in silico and ADME/T analyses to examine how active compounds from onions interact with the 5-alpha-reductase enzyme.
1 citations
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January 2019 in “Journal of Pharmacognosy and Phytochemistry” This article reviews the potential health benefits of onions, highlighting their anti-inflammatory, anticancer, and antioxidant properties, but does not report any new clinical results.
1 citations
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April 2009 in “한국생물공학회 학술대회” In this study, onion (Allium cepa) extracts promoted hair growth in an alopecia model in mice, with the effect appearing unrelated to the presence of the polyphenol quercetin.
May 2026 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this study, topical red onion ethanol extract significantly restored cutaneous antioxidant and pro-angiogenic markers in UV-B-exposed rats, enhancing SOD and VEGF levels dose-dependently, but did not influence hair length, suggesting potential as an adjunct for hair photoaging.
November 2025 in “Universidad Industrial de Santander” In this study, a hair cleansing tonic using Aloe vera and red onion was developed and found effective for promoting hair growth according to sensory tests by 30 panelists in Puerto Wilches, Santander, meeting microbiological safety standards.
October 2025 in “Indonesian Journal of Pharmaceutical Science and Technology” This review highlights the significant antidiabetic activity of Allium ascalonicum (shallot), attributed to its flavonoid compounds like quercetin, in reducing blood glucose levels across various studies, while calling for further research to confirm its safety and efficacy as a diabetes treatment.
January 2025 in “International Journal of Pharmacognosy and Pharmaceutical Research” This study found that hydroalcoholic extracts of Bacopa monnieri demonstrated significant antimitotic activity in an Allium cepa model, suggesting potential comparable effects to the standard drug methotrexate.
November 2024 in “Apple Academic Press eBooks” In this chapter, the authors emphasize the significant therapeutic roles attributed to Allium tuberosum due to its rich phytochemicals, detailing potential benefits against various conditions like diabetes, cancer, and liver dysfunction, as well as its applications in anticoagulation, muscle cell proliferation, and sensory perception mediation.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
May 2023 in “Journal of Ethnopharmacology” In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.
April 2022 in “Journal of applied science and environmental management” This study found that Aframomum melegueta seed extract improved wound healing in albino rats, with treated groups showing smaller wound sizes and formation of new tissues compared to controls.
December 2021 in “Jurnal ilmiah Manuntung” This study tested a hair tonic containing gotu kola and garlic extracts on rabbits, finding that the formulation with 5% gotu kola and 0.04% garlic showed promising hair growth results and remained stable during storage.
June 2021 in “Journal of emerging technologies and innovative research” This article reviews the potential hair-protective effects of Onion and Aloe vera against damage from hair dyes but reports no new experimental results.
February 2020 in “International research journal of pharmacy” This study suggests that a topical emulsion containing Camellia sinensis and Allium cepa extracts may show promise for treating alopecia areata in Wistar rats.
January 2020 in “JoLS Journal of Life Sciences” This study found that a mixture of Red-BCQ and Agnex extract promoted greater hair growth and antioxidant effects in C57BL/6 mice compared to other groups, including minoxidil treatment.
2 citations
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November 2011 in “Journal of Infection” This case study presents an asthma patient with H1N1 pneumonia who developed invasive Aspergillosis despite avoiding steroids, suggesting that factors other than steroid use can contribute to IA in such patients.
October 2025 in “Burns & Trauma” This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
74 citations
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September 2006 in “Cell Cycle” This review examines the role of Hairless, a nuclear receptor corepressor, in regulating Wnt signaling during hair cycling and reports no new clinical results.
68 citations
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September 2018 in “Trends in Cell Biology” This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.
June 2026 in “International Journal of Molecular Sciences” This study found that shallot (Allium ascalonicum) extracts reduced oxidative stress in human nasal epithelial cells caused by PAH exposure by decreasing ROS generation, suppressing lipid peroxidation, and restoring SOD activity, with quercetin being a key antioxidant component.
May 2025 in “Journal of Experimental Pharmacology” This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders.
October 2024 in “Veterinary World” This study reported that shallot extract showed strong antimicrobial activity, and supplementation with shallot powder may enhance broiler chicken growth, immune response, and microbiome balance.
April 2024 in “Iranian Journal of Microbiology” Shallot extract from Palu Valley can effectively kill Salmonella typhi.
April 2025 in “Journal of Ethnopharmacology” January 2017 in “Journal of Asian Scientific Research” This study observed that onion plants in Gilgit had faster growth and larger bulb sizes compared to those in Hunza, Gilgit-Baltistan.