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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Advanced human skin models improve drug development and could replace animal testing.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

No cure for female pattern hair loss, but various effective treatments exist.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Semecarpus anacardium Linn. has many medicinal benefits.

A new type of sudden, complete female hair loss was found, with most patients fully recovering within 6 months without needing steroid treatment.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.