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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The Rotterdam Study aims to understand various diseases in older adults.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.