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Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Treat scalp and beard fungal infections early with oral antifungal medication and sometimes topical therapy, avoiding unnecessary allergy tests and surgery.

Oral zinc sulphate reduces dark hair color in mice.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

CD3+ T-cell presence is a reliable marker to tell apart alopecia areata from pattern hair loss.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.

Successful surgical hair restoration requires careful planning, precise execution, and proper aftercare, using techniques like follicular unit transplantation and correct hair angling for best cosmetic results.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.