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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Nerves are crucial for the regeneration of various body parts in many animals.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

PLD is an effective and safer alternative for treating breast cancer.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.