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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil was first made for high blood pressure, but it was later found to help hair growth.

Glycerin in hand cream can cause allergic skin reactions.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

Researchers made minoxidil efficiently using cobalt ferrite nanoparticles as a reusable catalyst.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

ACBP is crucial for healthy skin in mice.

Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.

Allium hookeri extract may help promote hair growth and protect cells from damage.

Compound 4 is a promising treatment for hair loss with low toxicity.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Shampoos clean hair mainly with surfactants and have added ingredients for extra benefits.

Pharmacy-sold shampoos tend to have fewer allergens compared to those sold in other stores.

The document says biodegradable cosmetics and packaging are better for the environment and user experience.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.