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In this study, researchers successfully developed a 3D printed alginate-gelatin composite hydrogel scaffold characterized by high porosity and potential applications in drug delivery and screening, particularly for neurodegenerative diseases like Alzheimer's.

The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.

This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.

This study reports that the newly developed SA-Ca(II) hydrogel has tunable mechanical properties, high biocompatibility, and potential applications in wearable protections and stimuli-responsive electronics.

This article reviewed literature and found that Alginate-Chitosan-Fucoidan sponges may offer effective alternatives for wound dressing due to their enhanced wound healing abilities, attributed to good hemostatic and antibacterial properties, as well as excellent elasticity.

A new method was developed to detect pesticide residues on apples without damage.

This study reported that newly developed quaternary ammonium chitosan/carboxymethyl starch/alginate sponges effectively inhibit bacterial growth and promote rapid hemostasis in wound management after tooth extraction in animal models, showing significant promise for clinical use in preventing complications like dry socket.

In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.

This study evaluated a new composite material made from PLA, ALG, ZnS, and HT for blood-contacting applications, finding it improved surface characteristics and displayed anticoagulant properties and high biocompatibility with no genotoxic effects on blood and skin cells.

This study reports that PRP-loaded bioactive fibrous hydrogels significantly enhance wound healing in diabetic foot ulcers by reducing inflammation and promoting tissue growth, with reduced administration frequency compared to standard PRP gel.

In this study, researchers explored the use of natural materials in scaffold construction for dental bone preservation, suggesting it could offer better biocompatibility and bone regeneration compared to traditional grafting methods.

This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.

In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.

This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.

This study found that silk fibroin gel induced more pro-regenerative macrophages and hair follicle stem cells, leading to almost scarless skin regeneration compared to alginate gel.

This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.

This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.

This review outlines the development and functional requirements of modern wound dressing materials and describes preparation methods and product performance, but reports no new clinical findings.

This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study explored the use of manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (MCSA hydrogels) for treating melanoma and promoting wound healing, finding that these hydrogels effectively ablate melanoma under near-infrared irradiation and enhance vascular endothelial cell activity for tissue regeneration.

This study found that transplanted microencapsulated dermal papilla cells in rat footpads can regenerate hair follicles and sebaceous gland structures, suggesting a potential substitute for fresh dermal papillae cells.

This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.

In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.

This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.

This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.

This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.

This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.