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    Glossary Aldo-Keto Reductase Family 1 Member C3

    enzyme involved in hormone metabolism affecting hair growth and alopecia

    Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) is an enzyme that plays a crucial role in the metabolism of steroids, prostaglandins, and other compounds. It is involved in the conversion of hormones like testosterone and estrogen, which can influence various physiological processes, including hair growth and the development of conditions like alopecia.

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    Research 30 of 226

    1. Unravelling the link between insulin resistance and androgen excess University of Birmingham Institutional Research Archive (University of Birmingham) · 2015
    2. Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review Expert opinion on therapeutic patents · 2017 · 70 citations
    3. Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur Scientific reports · 2023
    4. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    5. Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis 2024
    6. Baiting Proteins with C<sub>60</sub> ACS Nano · 2010 · 106 citations
    7. MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis European Journal of Endocrinology · 2018 · 16 citations
    8. Steroidogenesis in steroid related cancers University of Birmingham Institutional Research Archive (University of Birmingham) · 2016
    9. HMGB1 promotes hair growth via the modulation of prostaglandin metabolism Scientific Reports · 2019 · 12 citations
    10. Proteomics as a tool to improve novel insights into skin diseases: what we know and where we should be going Frontiers in Surgery · 2022 · 3 citations
    11. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    12. Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives 2002 · 233 citations
    13. Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a Journal of Dermatological Science · 2010 · 29 citations
    14. The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites Medicines · 2018 · 19 citations
    15. Bimatoprost for the treatment of eyelash, eyebrow and scalp alopecia Expert Opinion on Investigational Drugs · 2017 · 38 citations
    16. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations
    17. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis Nature Reviews Endocrinology · 2011 · 991 citations
    18. 9. Immunology and Genetics Medical & surgical dermatology · 2009
    19. Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women Clinical Endocrinology · 2025 · 3 citations
    20. Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist Journal of nanobiotechnology · 2023 · 6 citations
    21. Polycystic Ovary Syndrome and Oxidative Stress—From Bench to Bedside International journal of molecular sciences · 2023 · 6 citations
    22. Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition Communications biology · 2024
    23. ENZYMES British journal of pharmacology · 2011 · 1 citations
    24. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    25. Ovine placental steroid synthesis and metabolism in late gestation† Biology of reproduction · 2018 · 9 citations
    26. The profile of steroid hormones in human fetal and adult ovaries Reproductive Biology and Endocrinology · 2024 · 11 citations
    27. Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer International Journal of Molecular Sciences · 2020 · 45 citations
    28. Androgens and ovarian function: translation from basic discovery research to clinical impact Journal of Endocrinology · 2019 · 55 citations
    29. Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review Pharmacological Reviews · 2022 · 49 citations
    30. Light Pollution and Oxidative Stress: Effects on Retina and Human Health Antioxidants · 2024