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Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

DA-9401 helps protect rat testis from finasteride damage.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

A mix of sulforaphane, L-menthol, and dexpanthenol could help increase hair growth and reduce hair loss.

Father's finasteride use may affect son's fertility and testicular function.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.