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Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Ozone therapy might improve cancer treatment and reduce its side effects.

Arctiin helps protect hair cells from damage and death caused by oxidative stress.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Use specific tools to measure quality of life in alopecia areata patients and improve future treatments.

Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.

Most people with Alopecia Areata don't get treatment within a year; it's costly and often comes with other health issues.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

Eating vitamin A affects hair growth and health by changing cell signals in mice.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.