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Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

A boy with Sjogren-Larsson syndrome has skin and muscle symptoms due to a specific enzyme deficiency.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Proteomics combined with other technologies can lead to a better understanding of skin diseases.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Higher fluence in hair removal damages hair follicles more, while lower fluence mimics natural hair regression, with long-term IPL treatments effectively reducing hair.

Targeting colon cancer stem cells might lead to better treatment results.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Vitamins A, B7, C, D, and E are essential for healthy hair growth and preventing damage.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.