17 citations
,
January 2021 in “Dermatology and Therapy” This review discusses laser-assisted drug delivery for enhancing topical treatment efficacy in various dermatological and medical applications but reports no new clinical results, emphasizing the need for further research to optimize its use.
17 citations
,
June 2017 in “British Journal of Dermatology” This review examines the interaction between hedgehog and Wnt/β-catenin signalling in hair follicles and basal cell carcinoma, linking Hh pathway inhibition to both tumor regression and alopecia.
17 citations
,
August 2011 in “Current Medicinal Chemistry” This review summarizes recent advancements in steroidal 5α-reductase inhibitors for benign prostatic hyperplasia and reports no new clinical results.
16 citations
,
June 2021 in “Journal of Dermatological Treatment” This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
16 citations
,
July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
16 citations
,
December 2018 in “ACS Biomaterials Science & Engineering” This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.
16 citations
,
September 2015 in “Journal of Ethnopharmacology” This review examines the long-standing use of "Dictamnus" in traditional medicine, highlighting the promising potential of D. albus and D. hispanicus as herbal drug candidates, but presents no new experimental findings.
15 citations
,
August 2020 in “American Journal of Pathology” This study found that insulin promotes corneal epithelial wound healing and nerve recovery in diabetic mice through Wnt signaling, suggesting its potential as a protective factor for diabetic corneal damage.
15 citations
,
July 2019 in “Lasers in surgery and medicine” This study found that 1,540 nm fractional erbium-glass laser treatment combined with topical minoxidil significantly increased hair regrowth in alopecia areata patches compared to minoxidil alone, with response rates of 60% versus 16%, though the long-term effects remain unknown.
15 citations
,
November 2015 in “Pharmacopsychiatry” This review discusses sexual dysfunction as a side effect of α-blockers and 5-ARIs for BPH/LUTS, highlighting methodological flaws in existing studies and the need for more rigorous research.
14 citations
,
January 2025 in “AAPS PharmSciTech” This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.
14 citations
,
June 2019 in “BMC infectious diseases” This study presents the first reported case of kerion-type scalp mycosis caused by Aspergillus protuberus, emphasizing the importance of mycological examination when diagnosing unusual scalp infections, especially in children.
14 citations
,
January 2017 in “Elsevier eBooks” This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.
14 citations
,
August 2016 in “Journal of nanomedicine research” This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.
14 citations
,
April 2014 in “International Journal of Cosmetic Science” This article discusses the multifactorial etiopathogenesis of acne vulgaris, highlighting the roles of sebum production, keratosis, bacterial development, and inflammatory mediators, but reports no new clinical results.
13 citations
,
July 2024 in “Heart Failure Reviews” This review compiles data on how the apelinergic system may protect against heart damage caused by doxorubicin cancer treatment, suggesting its potential to mitigate cardiotoxicity, though further research in chronic models is needed to confirm these effects and mechanisms.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.
13 citations
,
November 2019 in “Scientific reports” This study found that inhibiting 5α-reductase in molluscs provokes a specific shell morphology, suggesting gastropods might have unique 5α-reductase substrates absent in vertebrates.
13 citations
,
December 2012 in “Cells” This study describes how manipulating the actin cytoskeleton, particularly through the gelsolin family proteins, may enhance regenerative healing in mammals, suggesting potential therapeutic pathways for improved wound repair.
13 citations
,
August 1995 in “Australasian Journal of Dermatology” This study found that hair canal and follicle diameters, outer root sheath area, and terminal-to-vellus hair ratios were significantly reduced in androgenetic alopecia patients compared to normal controls.
12 citations
,
January 2024 in “Editora In Vivo eBooks” This case report from the study describes a dog suffering from dermatophytosis caused by Microsporum canis, presenting with alopecia on the neck and ear, illustrating the zoonotic risk of these fungal infections in both animals and humans, particularly in hot and humid climates.
12 citations
,
November 2022 in “Archives of Dermatological Research” This review summarizes existing and new cases of generalized pustular psoriasis and acute generalized exanthematous pustulosis associated with COVID-19, noting that over half lacked a known drug trigger.
12 citations
,
March 2020 in “Journal of Bioactive and Compatible Polymers” This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
11 citations
,
March 2025 in “Environmental Monitoring and Assessment” This review discusses how faecal pollution contributes to antimicrobial resistance in surface water and highlights the need for standardized methods and better wastewater management but reports no new clinical results.
11 citations
,
January 2022 in “Theranostics” In this study, Wnt4 was identified as a key factor in cardiac repair, where its regulation in cardiac fibroblasts improved cardiac function and revascularization following ischemic reperfusion injury.
11 citations
,
December 2020 in “Notulae botanicae Horti Agrobotanici Cluj-Napoca” This study found that arbuscular mycorrhizal fungus inoculation and shading improved tea seedlings' growth, nutrient absorption, and stress resistance by enhancing root biomass and regulating phytohormone levels and gene expression.
11 citations
,
June 2012 in “Human Reproduction Update” This review discusses recent advancements in female contraception and covers topics like adapted regimens, non-invasive sterilization, and the promise of new methods, but it reports no new clinical findings.
10 citations
,
June 2024 in “American Journal of Clinical Dermatology” This review highlights that while sonidegib and vismodegib offer promising treatment options for advanced basal cell carcinoma, their use is often limited by treatment-emergent adverse events, which can be managed through protocol modifications and supportive interventions.
10 citations
,
June 2021 in “Primates” This study found that wild geladas in Ethiopian crop areas experienced higher levels of human disturbance and health issues, such as increased parasitic infections, compared to those in pasture areas.
10 citations
,
May 2021 in “Expert Opinion on Drug Delivery” This study found that CoQ10 formulated in transethosomes showed improved penetration and a better clinical response in treating androgenic alopecia compared to CoQ10 solution.