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Human skin can make serotonin and melatonin, which help protect and maintain it.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Mannosylerythritol lipids are good for skin and hair care products.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

New treatments for male hypogonadism are effective and should be personalized.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.