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Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.

Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

Anti-glycation treatments might slow skin aging, but more research is needed.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Scalp reduction gives the most natural result for significant crown baldness, despite potential complications, and a systematic approach to surgical hair restoration results in few complications and high graft survival.

Most people who volunteered for a health study had medical issues, showing the need for careful screening before trials.

Early balding in men is linked to metabolic syndrome, so screening is important for prevention.

Men with severe hair loss may have poorer sperm quality.

The young woman with epilepsy became seizure-free after finding the right combination of medications.

Black and Hispanic women are more likely to have alopecia areata than white women.

Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.

Many Iraqi patients had skin problems at the site where a vein was taken for heart surgery.

A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.

Androgenetic alopecia is common in South-West Nigeria, affecting more men than women, with stress worsening the condition.

There's a significant link between the severity of Seborrheic Dermatitis and the pattern of hair loss in people with a family history of hair loss.

A woman thought to have rosacea was actually suffering from Frontal Fibrosing Alopecia, a hair loss condition. Despite treatment, her condition didn't change, showing the importance of accurate early diagnosis.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Caffeine can damage hearing cells and affect hearing recovery after ear trauma.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

High BMI worsens hair growth in women with PCOS.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Genetics and nutritional deficiencies are key factors in premature graying of hair.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.