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Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

Hair loss linked to higher heart disease risk in both men and women.

DHT may increase the risk of heart disease and death in elderly men.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Doctors need to be better prepared to assess and treat obesity in patients.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Obese women with PCOS are more likely to have fatty liver disease.

People with lichen planus have higher bad cholesterol and lower good cholesterol, increasing their risk for heart disease.

Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Asian immigrant mothers in Leicestershire need better obstetric care to reduce higher perinatal mortality risks.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.