50 citations
,
May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
49 citations
,
October 2014 in “International Scholarly Research Notices” This review explores the medicinal properties of Eclipta alba and its phytoconstituents and reports their potential for developing new drugs, but presents no new research results.
36 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” In this animal study, rats given high doses of ethynylestradiol showed dose-related estrogenic effects, delayed tumor onset in females, and no overall increase in tumor incidence compared to controls.
28 citations
,
July 2021 in “Pharmaceutics” This study found that Morus alba root extract activates β-catenin in hair follicle dermal papilla cells, promoting the transition to the anagen phase and enhancing hair growth factor secretion.
24 citations
,
December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
24 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” This study found that feeding norethindrone acetate to albino rats over two years caused various dose-related health effects, such as growth retardation and liver changes, but did not increase overall tumor incidence.
19 citations
,
January 2009 in “Journal of Young Pharmacists” This study found that the alcoholic extract of Eclipta alba exhibited dose-dependent antianaphylactic effects in animal models, possibly due to membrane stabilization and reduced histamine release.
13 citations
,
October 2017 in “Biomedicine & Pharmacotherapy” In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.
11 citations
,
May 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This review summarizes the phytomedicinal importance of Eclipta alba in Ayurvedic and folk medicine, particularly its use for hair growth and various biological properties, without reporting new clinical results.
9 citations
,
June 2014 in “Nutrition and Cancer” This study found that hydro-alcoholic Eclipta alba extract may have anticancer and multidrug resistance-reversal effects in animal models, suggesting potential as an adjunctive agent in tumor chemotherapy.
6 citations
,
August 2024 in “BMC Ophthalmology” This study identified multiple genetic variants in Pakistani families with oculocutaneous albinism, including two novel variants, enhancing understanding of its genetic basis and aiding better management and counseling.
6 citations
,
May 2018 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study found that adjusting plant growth conditions, such as the use of elicitors like yeast extract and methyl jasmonate, increased wedelolactone production in Eclipta alba cell suspension culture.
5 citations
,
October 2018 in “Journal of Drug Delivery and Therapeutics” This study found that Eclipta alba may protect against scopolamine-induced memory deficits in mice by reducing brain acetylcholinestrase activity and oxidative stress.
5 citations
,
May 2016 in “Jahangirnagar University Journal of Biological Sciences” This study demonstrated that the most effective method for inducing multiple shoots and root development in Eclipta alba involved specific concentrations of plant hormones on MS medium, resulting in healthy, flowering plantlets.
5 citations
,
March 2012 in “Clinical and Experimental Dermatology” A woman experienced temporary hair loss after taking albendazole, which resolved on its own within 3 months.
4 citations
,
March 2019 in “Journal of Pure and Applied Microbiology” This study investigated the anti-inflammatory effects of a 940nm diode laser in Wistar rats with carrageenan-induced arthritis and found that a 74J/cm² energy density significantly reduced edema and restored function, whereas 171J/cm² neared thermal exposure limits for the skin.
3 citations
,
March 2017 in “International Journal of Ayurvedic Medicine” This review discusses the ethnomedicinal claims, chemical composition, and pharmacological profile of Eclipta alba Hassk., reporting no new clinical results but suggesting future research for traditional medicine validation.
2 citations
,
January 2020 in “Journal of Pharmacognosy and Phytochemistry” This article reviews the medicinal significance of the Eclipta alba plant in India and its therapeutic properties, but reports no new clinical results.
2 citations
,
July 2017 in “Deleted Journal” This review discusses the memory enhancing activity of the ethanolic extract of Eclipta alba and reports no new clinical results.
1 citations
,
November 2023 in “Indian Journal of Science and Technology” In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
1 citations
,
July 2023 in “International Journal of Pharmaceutical Sciences and Drug Research” This study developed an effective and reliable HPTLC method for the simultaneous measurement of linoleic acid and oleanolic acid in Eclipta alba.
1 citations
,
February 2021 in “Journal of Natural Remedies” This study found that a combination of Ficus religiosa and Morus alba extracts promoted hair growth and Hair Follicle regeneration in a mouse model of hair loss by inducing the anagen phase and upregulating stem cell-associated genes.
1 citations
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January 2020 in “International journal of research in pharmacy and chemistry” This review provides an overview of the ethnomedicinal uses, chemical composition, and pharmacological profile of Eclipta alba Hassk and presents no new clinical findings.
This review discusses the traditional use of Eclipta alba in Ayurvedic medicine for liver disorders, hypertension, and notably for stimulating hair growth, but reports no new clinical results.
1 citations
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January 2017 in “Pharmaceutica Analytica Acta” This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
1 citations
,
January 2016 in “Der pharmacia lettre” This study found that shampoo formulated with Eclipta alba extracts may promote hair growth and act as an antidandruff agent due to its antifungal activity against Malassezia.
1 citations
,
January 2012 in “Ancient Science of Life” This study found that the ethanol extract of Eclipta alba significantly reduced gastric lesions and enhanced gastroprotective activity in ulcer-induced rats, suggesting potent antisecretory effects potentially linked to antioxidant properties.
July 2025 in “Journal of Research in Siddha Medicine” This study investigated the sub-acute toxicity of Eclipta alba extract in Wistar albino rats, finding generally comparable hematological and biochemical parameters to controls, but noted mild morphological liver and kidney changes at the highest dose, highlighting a key area for further safety research.
August 2026 in “Plant Science Today” This review synthesizes data on Eclipta alba, highlighting its traditional use for liver, skin, and general health, supported by preclinical evidence of hepatoprotective and other beneficial activities, while noting the need for more rigorous toxicological and clinical safety studies to substantiate its therapeutic applications.
June 2026 in “International Journal of Plant & Soil Science” This narrative review examines the traditional uses and pharmacological properties of Eclipta alba, emphasizing its potential benefits like hepatoprotective and hair growth-promoting effects, but highlights the need for more clinical validation and a focus on preserving traditional knowledge.