4 citations
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October 2003 in “PubMed” This study in a rat model found that dietary rehabilitation with a high protein diet reversed symptoms of kwashiorkor, suggesting a role for free radicals in its development.
3 citations
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January 2013 in “Egyptian Liver Journal” In this study, researchers found a significant prevalence of nonalcoholic fatty liver disease in Egyptian women with polycystic ovary syndrome, with insulin resistance being a key predictive factor.
3 citations
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March 2002 in “Linchuang pifuke zazhi” This study analyzed clinical manifestations of dermatomyositis in 18 patients, reporting common symptoms such as skin rash, proximal muscle weakness, and elevated serum markers, with treatment typically involving prednisolone and hydroxychloroquine.
2 citations
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August 2020 in “Journal of Nutritional Science and Vitaminology” In this study, yellow Chinese chive extract was observed to protect against acetaminophen-induced liver toxicity in mice by enhancing antioxidant pathways and reducing liver injury markers.
January 2026 in “International Journal of Biological Macromolecules” This study used a new multimolecular spectral method to uncover structural differences in hair keratin from individuals with androgenetic alopecia compared to healthy individuals, identifying potential biomarkers and providing insights for developing new treatments.
May 2024 in “Lithuanian University of Health Sciences” This study, conducted on 17 dogs with hyperadrenocorticism in Germany, concluded that while common symptoms like polyuria and polydipsia were observed in all cases, clinical signs and blood parameters did not significantly correlate with diagnostic test results for the condition.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AP-2α and AP-2β transcription factors are crucial for maintaining adult skin homeostasis, with their inactivation in keratinocytes leading to impaired differentiation, hair abnormalities, and inflammation, highlighting their key regulatory roles.
October 2023 in “Journal of pharmaceutical investigation” In this study, researchers found that among healthy Korean males, the clearance of finasteride was about 34% lower in individuals with the CYP3A5*3 homozygous allele compared to other genotypes, suggesting dosage adjustments may be necessary considering CYP3A5 and ALT levels to avoid adverse effects.
September 2023 in “Translational medicine reports” This case study reported that an 18-year-old woman ingested a large amount of topical minoxidil, leading to symptoms like low blood pressure, increased heart rate, and elevated liver enzymes, but recovered fully after treatment. Minoxidil toxicity may rarely cause abnormal liver enzyme levels.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study used machine learning to identify molecular predictors of drug response in alopecia areata, suggesting a tool for predicting treatment efficacy based on gene signatures.
March 2017 in “Iraqi Journal of Pharmaceutical Sciences” This study found that Iraqi male bodybuilders abusing anabolic androgenic steroids experienced significant changes in sex hormones, liver and kidney function, and lipid profiles compared to non-AAS-using controls.
January 2009 in “Side effects of drugs annual” This chapter reviews drugs affecting blood coagulation and details the increased hemorrhage risk associated with warfarin interactions, liver disease, heart failure, and antiphospholipid antibodies but reports no new clinical results.
15 citations
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June 2018 in “Life Sciences” This study found that Diabetex significantly improved wound healing and reduced fasting blood sugar in diabetic rats, showing potential as a safe and economic treatment strategy for diabetic-resistant wounds.
10 citations
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February 2007 in “Clinical techniques in small animal practice” This review discusses the etiology and clinical findings of atypical hyperadrenocorticism in dogs due to sex steroid imbalance and explores various treatment options, but reports no new results.
April 2024 in “Current research in nutrition and food science” This study found that a food supplement improved skin moisturization, elasticity, and thickness, reduced telogen hair density, and enhanced nail status in women with mild-to-moderate aging signs after 84 days.
17 citations
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May 2013 in “Journal of Investigative Dermatology” Mutations in β1 integrins cause embryonic death but have milder effects on skin.
9 citations
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January 2014 in “Molecular Genetics and Metabolism Reports” This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.
9 citations
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January 1981 This study found that the alkaline degradation process of hair keratin using nucleophilic reagents led to different proportions of reaction products compared to wool, particularly more lanthionine and lysinoalanine residues.
29 citations
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June 2010 in “The Journal of Dermatology” This report documents a novel alanine to valine substitution in the GJB2 gene in a Japanese girl with severe keratitis–ichthyosis–deafness syndrome, suggesting a potential link to her severe recurrent infections and immunodeficiency.
January 2002 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
37 citations
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August 2011 in “Journal of Bone and Mineral Research” This study reported a case of hereditary vitamin D–resistant rickets caused by a single heterozygous missense mutation in the VDR gene, showing dominant-negative effects and reduced response to 1,25-dihydroxyvitamin D3.
32 citations
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September 2004 in “BMJ” This review discusses public perceptions of aspartame's health risks and benefits and reports no evidence supporting claims that it is linked to cancer, depression, or other health issues.
August 2023 in “Fermentation” This review discusses the potential of metabolic engineering to enable sustainable industrial-scale production of L-aspartate and its derivatives, detailing current microbial production progress, limiting factors, and future prospects with emerging technologies in synthetic biology.
July 2023 in “Письма в Вавиловский журнал генетики и селекции” This review article discusses studies showing that extracellular nucleic acids play a role in tissue regeneration by triggering sterile inflammation through endosomal toll-like receptor activation, but notes that the regulatory transition from inflammation to proliferation phases remains incompletely understood.
94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.
34 citations
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September 2010 in “Clinical and Experimental Dermatology” This study identified a new heterozygous mutation in the connexin 26 gene (c.263C>T; p.Ala88Val) in a premature neonate with KID syndrome, who later died from complications.
33 citations
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October 2005 in “Journal of Investigative Dermatology” A specific gene mutation causes sparse, brittle hair in a family.
14 citations
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March 2021 in “Journal of Pediatric and Adolescent Gynecology” In teens with Polycystic Ovary Syndrome and obesity, issues related to metabolism, skin, and mental health are common, and a clinic with various specialists can provide care for most of these problems.
9 citations
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August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
3 citations
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February 2024 in “Patient Preference and Adherence” In this study, the authors suggest that patient safety with isotretinoin in Palestine can be improved by adapting pharmacy and medical practice protocols to better educate patients and ensure adherence to safety monitoring and laboratory ordering.