research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
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research The Current Role of Laser and Light Sources in the Treatment of Male and Female Pattern Hair Loss
Laser/light treatments for hair loss are popular but lack scientific data proving effectiveness.
research Micronutrient Status in Patients Receiving Home Parenteral Nutrition
One-third of patients on home nutrition had micronutrient deficiencies, with iron deficiency being most common, but serious issues were rare.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research French Administrative Health Care Database (SNDS): The Value of Its Enrichment
Enriching the French health care database with external data greatly improved its usefulness.
research Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency
A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study
High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
research The Treatment of Acne: The Role of Combination Therapies
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Jaw Wiring in Treatment of Obesity
Jaw wiring helps with weight loss but long-term habits are needed to keep it off.
research Use of an 800-nm Pulsed-Diode Laser in the Treatment of Recalcitrant Dissecting Cellulitis of the Scalp
The document does not conclude the effectiveness of the 800-nm pulsed-diode laser for treating scalp cellulitis.
research Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
research Minoxidil in Severe Hypertension: Value When Conventional Drugs Have Failed
Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
research Executive Summary: Heart Disease and Stroke Statistics—2011 Update
Cardiovascular disease deaths decreased but still caused one-third of U.S. deaths in 2007, with high rates of hypertension, smoking, obesity, and diabetes.
research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research The Skin in Pregnancy: A Review of Normal Changes
Pregnancy can cause normal skin changes that usually go away after childbirth and don't need treatment.
research Alopecia in the United States: Outpatient Utilization and Common Prescribing Patterns
Alopecia areata causes significant emotional distress, including high rates of depression and anxiety.
research Fertility Evaluation of Infertile Women: A Committee Opinion
The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.
research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Fluoroquinolone-Induced Serious, Persistent, Multisymptom Adverse Effects
Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
research Interest of High-Dose Pulse Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata: A Retrospective Case Series
Combining high-dose corticosteroids with methotrexate may be effective and safe for severe alopecia areata.
research Neuregulin3 Alters Cell Fate in the Epidermis and Mammary Gland
Neuregulin3 affects cell development in the skin and mammary glands.
research PUVA Treatment of Alopecia Areata Totalis and Universalis: A Retrospective Study
PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.
research Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments
Hair proteins have weak spots in their α-helical segments.
research De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
research Beyond Vitiligo Guidelines: Combined Stratified/Personalized Approaches for the Vitiligo Patient
Personalized treatment plans improve vitiligo care.
research Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study
Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.