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      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.

      research Alopecia Mucinosa

      186 citations , October 1957 in “A M A Archives of Dermatology”
      This paper presents a collection of unusual cases observed over seven years, with detailed histological descriptions but no definitive diagnoses, aiming to encourage further discussion and understanding of the disease process.
      Alopecia Areata: Treatment Options and Efficacy

      research Alopecia areata

      182 citations , December 2017 in “Journal of the American Academy of Dermatology”
      This article reviews current and emerging treatments for alopecia areata, including Janus kinase inhibitors, highlighting variability in clinical outcomes and the lack of sustained remission.
      Guidelines for the Management of Alopecia Areata

      research Guidelines for the management of alopecia areata

      182 citations , October 2003 in “British Journal of Dermatology”
      These guidelines for alopecia areata management, prepared by the British Association of Dermatologists, provide evidence-based treatment recommendations and insights into the condition's epidemiology, diagnosis, and investigation.

      research Alopecia Areata in Aging C3H/HeJ Mice

      178 citations , June 1994 in “Journal of Investigative Dermatology”
      This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.
      Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing

      research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing

      176 citations , August 2015 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.
      Fetal Alcohol Syndrome: Current Status of Pathogenesis

      research Fetal Alcohol Syndrome: Current Status of Pathogenesis

      171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”
      The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

      research Rickets with alopecia: An inborn error of vitaminD metabolism

      170 citations , May 1979 in “˜The œjournal of pediatrics/˜The œJournal of pediatrics”
      This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.
      Frontal Fibrosing Alopecia: A Review of 60 Cases

      research Frontal fibrosing alopecia: A review of 60 cases

      166 citations , April 2012 in “Journal of The American Academy of Dermatology”
      This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
      Interventions for Alopecia Areata

      research Interventions for alopecia areata

      164 citations , April 2008 in “Cochrane library”
      This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.
      Decreased Serum Ferritin Is Associated With Alopecia in Women

      research Decreased Serum Ferritin is Associated With Alopecia in Women

      163 citations , November 2003 in “Journal of Investigative Dermatology”
      This study found that women with androgenetic alopecia or alopecia areata have significantly lower serum ferritin levels than those without hair loss, suggesting a potential link between these types of alopecia and decreased iron stores.

      research The autoimmune basis of alopecia areata: A comprehensive review

      162 citations , October 2014 in “Autoimmunity reviews”
      This review discusses alopecia areata, highlighting its autoimmune aspects, environmental triggers, and current treatment options, but reports no new clinical results; recent studies suggest JAK pathway intervention may offer therapeutic potential.

      research PROFILE OF ALOPECIA AREATA: A QUESTIONNAIRE ANALYSIS OF PATIENT AND FAMILY

      161 citations , March 1992 in “International Journal of Dermatology”
      This study analyzed survey responses from 800 alopecia areata patients and found a possible genetic association with increased insulin-dependent diabetes mellitus in relatives but not in the patients themselves.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Alopecia Areata: Overview and Treatment Options

      research Alopecia areata

      151 citations , February 2007 in “International Journal of Dermatology”
      This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
      The Role of Scalp Dermoscopy in the Diagnosis of Alopecia Areata Incognita

      research The role of scalp dermoscopy in the diagnosis of alopecia areata incognita

      150 citations , April 2008 in “Journal of The American Academy of Dermatology”
      This study found that videodermoscopy reveals distinct dermoscopic features in patients with alopecia areata incognita, aiding in biopsy decisions by identifying the appropriate sampling area and potentially avoiding unnecessary procedures.