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CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Wheat sprout extract boosts hair cell growth by activating specific proteins.

Photobiomodulation helps hair regrow in injured skin by aiding cell movement and secretion.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

PI3K/Akt pathway is crucial for hair growth and regeneration.

Pilose antler extracts help hair growth by activating hair follicle stem cells.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.

Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

Experts agree on how to manage sugar levels and skin reactions in patients taking the cancer drug alpelisib.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.