February 2022 in “Journal of Biomedical Nanotechnology” Shikonin, a small molecule, speeds up burn wound healing and hair growth by activating the PI3K/Akt pathway.
505 citations,
December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
[object Object] 30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
12 citations,
April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
11 citations,
September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
2 citations,
July 2023 in “International Journal of Molecular Sciences” BFNB could be a promising treatment for hair growth.
January 2024 in “Theranostics” Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
January 2022 in “SSRN Electronic Journal” LncRNA RP11-818024.3 helps hair growth and recovery in hair loss by boosting cell survival and reducing cell death.
April 2019 in “Journal of Investigative Dermatology” Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
April 2019 in “Journal of Investigative Dermatology” Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
14 citations,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
149 citations,
April 2004 in “Journal of Dermatological Science” Minoxidil boosts hair growth by increasing cell production and survival.
54 citations,
June 2008 in “Planta Medica” Hinokitiol may help treat hair loss by reducing inflammation and promoting hair growth.
49 citations,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
32 citations,
January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
28 citations,
October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
27 citations,
August 2015 in “Experimental Dermatology” Certain electric currents can promote hair growth by activating specific cell pathways.
25 citations,
September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
24 citations,
September 2005 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
21 citations,
January 2020 in “Pharmaceutical Biology” Salvia plebeia extract can stimulate hair growth.
17 citations,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
16 citations,
October 2019 in “Biological & Pharmaceutical Bulletin” Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
14 citations,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
14 citations,
September 2018 in “International Journal of Molecular Sciences” Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.
14 citations,
June 2018 in “Frontiers in pharmacology” Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
[object Object] 13 citations,
January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
12 citations,
September 2019 in “BioFactors” Ginkgolide B and bilobalide help mink hair grow by making skin cells healthier and boosting a key growth protein.
12 citations,
June 2017 in “Cell Cycle” Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.