2 citations
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August 2018 in “Journal of pharmacopolium” This study found that a combination extract of pandanus and sansevieria leaves at a 3:2 ratio showed better hair growth activity than either extract alone.
2 citations
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April 2016 in “Pharmaciana” This study found that a combination of 5% green tea leaf extract and 2.5% gotukola extract stimulated hair growth effectively, achieving a growth rate of 2.689 cm in 28 days.
1 citations
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October 2025 in “PLoS ONE” In this study, researchers found that overexpression of LncRNA RP11-818O24.3 in hair follicle stem cells promotes their proliferation, self-renewal, and differentiation while inhibiting apoptosis through the FGF2-mediated PI3K/AKT signaling pathway, suggesting potential therapeutic applications for hair loss treatment.
1 citations
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June 2023 in “Cells” This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.
1 citations
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April 2023 in “International Journal of Molecular Sciences” This review discusses advances in CRISPR/Cas9 variants and nanoformulations for cancer treatment, noting challenges and prospects for clinical application, but reports no new research results.
1 citations
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August 2019 In this study, a hair tonic formulation with 25% ethanol extract of mangkokan leaves showed effectiveness in promoting hair growth, as measured by significant differences in hair length and weight compared to the control.
1 citations
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January 2019 This study found that a hair tonic combining fragrant pandan and celery extracts increased hair length in guinea pigs, with the 1:5 concentration showing the best growth activity.
1 citations
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November 2017 in “JFL : Jurnal Farmasi Lampung” In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
In this network meta-analysis, the researchers reported that topical minoxidil 5% was the most effective off-label therapy for increasing hair density in men with androgenetic alopecia, while other treatments like melatonin and cetirizine showed potential benefits, highlighting a need for further comparative trials.
May 2026 in “Malahayati Nursing Journal” In this single-case study, a 36-year-old woman with skin aging issues experienced improvements such as reduced wrinkles, fresher appearance, enhanced hair and lip health, and increased menstrual blood flow after six facial acupuncture sessions aimed at addressing Lung Yin and Blood Deficiency.
March 2026 in “Calcified Tissue International” This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.
December 2025 in “Antibiotics” In this systematic review, researchers found that Tinea capitis in individuals aged 65 or older is frequently misdiagnosed, primarily affects women, and often presents with inflammatory symptoms; systemic antifungal therapy led to clinical cure in 91.2% of cases.
August 2025 in “International Journal of Molecular Sciences” This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.
August 2026 in “Frontiers in Pharmacology” This study found that dihydromyricetin may reduce fibrosis features in hypertrophic scars by affecting PI3K/AKT/mTOR signaling, but further research is needed to confirm causality.
August 2026 in “npj Regenerative Medicine” This study found that hair follicle micro-graft transplantation significantly improved scar remodeling outcomes in 40 patients, with greater reductions in scar volume, lower scar scores, and enhanced skin characteristics compared to punch excision alone, potentially due to activation of the PI3K-AKT pathway.
May 2026 in “Scientific Reports” In this study, researchers overexpressed Lrig3 in mouse skin and observed hair loss linked to changes in skin protein profiles and signaling pathways, suggesting a potential role for Lrig3 in maintaining skin homeostasis.
May 2026 in “Stem Cell Research & Therapy” This study found that exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) significantly promoted hair regrowth and follicle density in a mouse model of androgenetic alopecia, showing similar efficacy to minoxidil by activating pathways that improve follicular vascularization and dermal papilla cell function.
March 2026 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this in vitro study, the researchers found that garden balsam leaf extract serum showed no antifungal inhibition against Candida albicans, while the positive control, a 2% ketoconazole shampoo, demonstrated a strong effect.
In this study, applying a 5% concentration of pomegranate peel extract significantly enhanced hair growth on male rabbits, showing results comparable to the positive control using 2% Minoxidil, but higher concentrations or lower concentrations did not perform as well.
January 2026 in “Biospecies” In this study, a hair tonic containing black fungus extract was shown to have antifungal activity against Malassezia furfur, with the 70% extract concentration providing the strongest effect.
December 2025 in “Journal of Ovarian Research” This study found that multiple vitamins, including B6, increased the number of growing follicles in newborn mouse ovaries in vitro. VB6 promoted primordial follicle activation via the PI3K/Akt signaling pathway in both cultured mouse and human ovarian tissues.
October 2025 in “Cell Death and Disease” In this study, researchers developed two novel mouse models to investigate how CD271 deletion in keratinocytes affects skin homeostasis, finding that it leads to changes resembling dysplastic skin conditions with immune cell recruitment and inflammatory cytokine release.
October 2025 in “Journal of Cosmetic Dermatology” This study found that conventional treatments like oral dutasteride and topical/oral minoxidil are effective for male androgenetic alopecia, and it provides guidance on the relative efficacy of some alternative treatments, such as topical melatonin and rosemary oil, compared to these conventional therapies.
August 2025 in “Skin Appendage Disorders” This review highlights that while low-dose oral minoxidil appears well-tolerated in cancer patients post-chemotherapy, its use during active chemotherapy has shown potential benefits but remains under investigation, with preclinical studies suggesting a protective effect against chemotherapy-induced alopecia.
June 2025 in “Stem Cell Research & Therapy” In this study, researchers found that isoproterenol, an adrenergic β2 receptor agonist, promoted hair growth and hair follicle stem cell proliferation in models of androgenetic alopecia by modulating the PI3K/AKT/β-Catenin pathway, suggesting a potential new therapeutic strategy for hair loss.
January 2025 in “Nutrients” In this study, researchers found that specific genetic variations at loci rs1160312, rs6113491, and rs1041668 are independent risk factors for androgenetic alopecia in men, and these risks can be influenced by diet.
December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
August 2023 in “Jurnal Pharmacia Mandala Waluya” This study examined the effects of purified Albizia saponaria bark extract on hair growth in rabbits, finding that a 20% concentration of the extract increased hair weight significantly, though it was less effective than minoxidil.
June 2023 in “International Journal for Research in Applied Science and Engineering Technology” This research highlights the potential of emulgel as an advanced topical drug delivery system, offering improved efficacy for hydrophobic medications in treating dermatological conditions and a range of ailments with its dual release control mechanism of gel and emulsion.