research Clinical and Metabolic Characteristics of Males With Early-Onset Androgenetic Alopecia
Altered hormones and insulin resistance are common in young men with early hair loss and linked to more severe cases.
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research Effects of Skin Environmental Changes by Steam Towel, Ethanol, L-Menthol and Carpronium on the Drug Behavior in Minoxidil Nanoparticles-Applied Mice
Using a steam towel, l-menthol, and carpronium before applying minoxidil nanoparticles can increase its absorption and potentially improve hair growth.
research Long-Term Evaluation of Efficacy and Safety of Finasteride in Japanese Men with Androgenetic Alopecia: Summary of Three Investigations
Finasteride is effective and safe for long-term use in treating hair loss in Japanese men.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Expression of Signal Transducer and Activator of Transcription-3 in Androgenetic Alopecia: A Case Control Study
Higher STAT3 levels are found in hair loss areas, but not linked to hair loss severity.
research Investigation of Plasma Thiol/Disulfide Balance in Male Patients with Androgenetic Alopecia
Thiol/disulfide balance is normal in male AGA patients but shifts towards oxidative stress with emotional stress and low vitamin D.
research Serum Prostate Specific Antigen Levels in Women with Androgenetic Alopecia
Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.
research Finasteride Induced Clinical Ocular Toxicity
research In Vitro Hair Follicle Regeneration by Three-Dimensional Cell Culture Method Simulating In Vivo Cellular Organization
research Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption
Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
research The Human Sebocyte Culture Model Provides New Insights Into Development and Management of Seborrhoea and Acne
The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Hair Follicle Stem Cells: Insights from the 2003 Workshop
Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
research Prevalence of Dermatological Disorders in Japan: A Nationwide, Cross-Sectional, Seasonal, Multicenter, Hospital-Based Study
Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.
research Vitamin D Deficiency in Alopecia Areata
Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.
research The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
research Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019
Some people who recover from COVID-19 continue to have symptoms like fatigue and cough for over 120 days, and some experience hair loss about 59 days after getting sick.
research Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Combination of Topical Garlic Gel and Betamethasone Valerate Cream in the Treatment of Localized Alopecia Areata: A Double-Blind Randomized Controlled Study
Garlic gel with betamethasone cream significantly improves hair regrowth in alopecia areata.
research Comparing the Therapeutic Effects of Finasteride Gel and Tablet in Treatment of Androgenetic Alopecia
Finasteride gel is slightly more effective than the tablet for treating hair loss.
research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege
Hair follicle cells help protect against immune attacks by regulating T-cell activity.
research Effects of a Low-Dose Desogestrel-Ethinylestradiol Combination on Hirsutism, Androgens, and Sex Hormone Binding Globulin in Women with Polycystic Ovary Syndrome
Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.
research The Evaluation of Endothelial Function with Flow-Mediated Dilatation and Carotid Intima Media Thickness in Young Nonobese Polycystic Ovary Syndrome Patients; Existence of Insulin Resistance Alone May Not Represent an Adequate Condition for Deterioration of Endothelial Function
Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.
research Dermoscopic Findings in Scalp Psoriasis and Seborrheic Dermatitis: Two New Signs; Signet Ring Vessel and Hidden Hair
Two new signs, 'signet ring vessels' and 'hidden hairs,' help tell apart scalp psoriasis and seborrheic dermatitis.
research Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Interest of High-Dose Pulse Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata: A Retrospective Case Series
Combining high-dose corticosteroids with methotrexate may be effective and safe for severe alopecia areata.
research Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability
Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
research Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study
Calcipotriol cream can effectively and safely treat mild-to-moderate patchy hair loss.
research Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey
AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.