5 citations
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April 2024 in “JAAD International” AI can accurately measure hair loss severity in alopecia areata.
14 citations
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June 2022 in “British Journal of Dermatology” This study found that the Alopecia Areata Symptom Impact Scale (AASIS) is a better tool than the Alopecia Areata Quality of Life Index (AA-QLI) for assessing patient-reported outcomes in alopecia areata.
10 citations
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August 2011 in “Clinics” This article presents a dissenting opinion, arguing that the case described by Dr. Molina et al. was diffuse alopecia areata, not acute alopecia areata as claimed, emphasizing the importance of distinct clinical differences.
62 citations
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April 2008 in “Neurobiology of aging” This study identified a new genetic locus, ahl4, on distal Chromosome 10 that contributes to the early-onset, severe hearing loss in A/J mice compared to B6 mice.
March 2026 in “JID Innovations” In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that targeting both hormonal and immune pathways improved treatment outcomes in androgenetic alopecia patients with an under-recognized inflammatory component called PIILIF, which may contribute to treatment resistance.
December 2025 in “Clinical Cosmetic and Investigational Dermatology” In this report, a unique female presentation of IFAP syndrome is described, featuring musculoskeletal contractures but no photophobia, highlighting the importance of early detection and multidisciplinary care to improve outcomes and prevent disability.
21 citations
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February 2024 in “JAMA Dermatology” This study identified multiple factors affecting the severity of alopecia areata, suggesting they could inform a tool for measuring disease impact and guide treatment selection.
19 citations
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January 2011 in “Clinics” This article reviews alopecia areata incognita, a rare condition mostly seen in young women, and discusses its similarities and differences with telogen effluvium; however, it reports no new clinical findings.
1 citations
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January 2020 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” This study found that Aminexil clinical 5 significantly reduced hair loss in men and women with mild alopecia and was well tolerated with high subject satisfaction.
This report presents a case of IFAP syndrome with the typical symptoms of alopecia universalis, severe photophobia, and follicular ichthyosis, but provides no additional clinical findings or conclusions.
14 citations
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June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.
2 citations
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May 2025 in “Diagnostics” This study found that ATR-FTIR spectroscopy combined with machine learning effectively differentiated alopecia areata patients from healthy controls with an AUC of 0.85, and also showed promise in predicting treatment response, particularly through alterations in the Amide I band.
1 citations
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March 2024 in “Skin health and disease” This study found that vibration assisted analgesia reduced pain during intralesional corticosteroid therapy for hair loss, enabling treatment in a broader range of patients, including those with needle phobia.
7 citations
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December 2021 in “European Respiratory Review” This review covers the current status of the interstitial pneumonia with autoimmune features (IPAF) category, pointing out the need for revision of its criteria to establish it as a standalone diagnostic term, but reports no new clinical findings.
40 citations
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August 2005 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this case report, a 3-year-old male with IFAP syndrome showed moderate improvement in skin symptoms and corneal erosions but no change in alopecia or photophobia after 6 months of acitretin therapy.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
December 2023 in “International Journal of Dermatology” This study reports that trichoscopy and histopathology can effectively diagnose alopecia areata incognito and differentiate it from telogen effluvium or androgenetic alopecia, aiding clinicians in better hair regrowth management.
13 citations
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January 2018 in “International Journal of Trichology” In this study, intralesional triamcinolone acetonide injections were associated with halting the progression of frontal fibrosing alopecia in female patients and showed minimal adverse effects, but the efficacy as sole therapy remains unclear pending further trials.
1 citations
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November 2022 in “International journal of trichology” This case report describes a 6-year-old girl with IFAP syndrome who showed good improvement in cutaneous symptoms after one month of acitretin treatment.
January 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study evaluated 129 patients with androgenetic alopecia and identified an inflammatory pattern of perifollicular infiltration linked to treatment resistance. Targeting both hormonal and immune pathways improved outcomes for 67% of patients, suggesting inflammation may play a role in some cases of stubborn hair loss.
2 citations
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March 2025 in “Journal of Translational Autoimmunity” This study reports that AhR pathway expression is significantly reduced in lymphocytes of alopecia areata patients, suggesting its potential as a diagnostic marker and therapeutic target.
16 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that intramuscular anti-IFN-γ significantly stabilized and promoted hair regrowth in alopecia areata patients with patchy, progressive hair loss, whereas those with total baldness showed more limited improvement.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, freezing gamma-irradiated amniotic fluid increased hair follicles and accelerated the transition to the anagen stage in rats, suggesting potential for treating hair loss safely and effectively.
November 2023 in “International Journal of Pharmaceutics” This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.
June 2025 in “British Journal of Dermatology” This study introduces ALUDWIG, an automated tool for assessing female androgenic alopecia severity from smartphone images, which may offer a more consistent alternative to current scoring methods like the Ludwig scale.
January 2011 in “Journal of Human Genetics” This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.
14 citations
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that serum MIF levels were significantly higher in patients with extensive alopecia areata compared to those with mild alopecia areata and healthy individuals.
September 2024 in “Skin Appendage Disorders” This case report describes a 21-year-old woman with circumscribed alopecia areata incognita, who experienced a sustained positive response to treatment with oral tofacitinib after conventional treatments frequently failed to provide lasting effects.
February 2017 in “International Journal of Research in Dermatology” This report describes a case of alopecia areata incognita in a 6-year-old child, marked by sudden diffuse hair loss without bald patches, typically observed in adults.