April 2026 in “Preprints.org” The study found that enhancing quercetin bioavailability with EubioQuercetin may amplify its anti-aging effects in mice by modulating the gut microbiota and improving intestinal barrier function.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
December 2025 in “International Journal of Molecular Sciences” In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.
September 2025 in “Cureus” This narrative review highlights recent advancements in anti-ageing cosmetic procedures, emphasizing personalized interventions that improve patient outcomes and quality of life. The review synthesized evidence from 144 articles to assess the effectiveness and potential side effects of surgical and non-surgical techniques for facial rejuvenation.
February 2025 in “Endocrine Reviews” In this review, the authors explored how various hormones, particularly IGF-1, GH, estrogens, retinoids, and melatonin, influence human skin aging, highlighting potential new avenues for anti-aging therapies beyond the currently utilized topical retinoids and estrogens.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, researchers found that frontal hair follicles in individuals with androgenetic alopecia show a higher biological age compared to occipital follicles, possibly due to decreased expression of the transcriptional repressor TRPS1 in frontal dermal papillae, which may influence follicle miniaturization.
June 2023 in “Skin Health and Disease” This editorial highlights recent progress in understanding chronic inflammatory skin diseases, leading to new treatments like JAK inhibitors for eczema and psoriasis, while emphasizing the journal's call for research on skin biology and aging.
January 2023 in “Zdravstvena zaštita” This review evaluates current research on how hormonal changes due to aging impact voice quality, concluding the vocal cords are sensitive to hormonal fluctuations throughout life but reports no new clinical results.
November 2022 in “Journal of Investigative Dermatology” This study found that dysregulation of the DNA damage response in stem cells is a common factor of aging, affecting tissues like the skin, brain, kidneys, and intestine.
November 2022 in “Journal of Investigative Dermatology” This study explores the role of cell competition in maintaining genomic quality in epidermal stem cells and proposes that this process might influence cancer development in skin tissues.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Kudo Anti-Aging Gummies, which are promoted as a natural supplement designed to reduce wrinkles, enhance hair and nail health, and improve skin appearance by restoring collagen, with results purportedly visible within 1-2 months.
November 2021 in “Plastic and Reconstructive Surgery” This supplement reviews advancements in the science of aging, including facial age simulation and stem cell applications for hair restoration, and reports no new clinical results.
November 2021 in “Plastic and Reconstructive Surgery” This supplement chronicles the 2020 Science of Aging Symposium, highlighting emerging discoveries in aging research, such as gene therapies and using AI for visualizing skin, without reporting new clinical results.
May 2021 in “Клітинна та органна трансплантологія” This review covers recent findings on skin aging, emphasizing how cellular senescence and changes in the microenvironment impair stem cell functions, affecting skin regeneration.
July 2020 in “RePub (Erasmus University, Rotterdam)” This thesis analyzed four skin aging features and their relationships with lifestyle, physiological factors, and genetics.
June 2020 in “International journal of research in dermatology” This study found that oral intake of choline-stabilized orthosilicic acid (ch-OSA®) significantly improved hair, skin, and nail health in the Indian population, with no reported side effects.
September 2018 in “PubMed” This review discusses the aging-related changes in hair properties, their impact on styling, and potential interventions, without providing new clinical results.
August 2018 in “Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)” This research observed that chronological age, rather than hearing loss, primarily affects the auditory cortex in aging, and found that brain aging in PolG mice mirrored that of wild-type counterparts, suggesting differential tissue sensitivity to mitochondrial dysfunction.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that age-related changes in scalp dermal fibroblasts, including increased MMP-1 and reduced ECM components, may significantly affect the hair follicle environment and contribute to hair aging.
January 2018 in “Elsevier eBooks” This chapter reviews Hutchinson–Gilford progeria syndrome as a model for studying aging but presents no new findings, covering its genetic basis, clinical features, and existing treatments.
This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
February 2016 in “Science” This research found that Foxc1 promotes quiescence in hair follicle stem cells and identified COL17A1 depletion, due to DNA damage, as a cause of hair thinning and loss during aging.
May 1999 in “Journal of Oral and Maxillofacial Surgery” The book provides practical guidance on cosmetic facial surgery for clinicians.
December 1989 in “PubMed” January 2023 in “Dermatology” This review summarizes biological links between aging and androgenetic alopecia, particularly focusing on cellular senescence, and discusses potential therapeutic strategies, but reports no new clinical results.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that ageing in women leads to significant structural and biological changes in the scalp hair follicle environment, which may affect hair growth.
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July 2005 in “Dermatologic surgery” This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in aging facial skin over 12 weeks.
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.