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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.