1 citations
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January 2004 in “The Internet Journal of Geriatrics and Gerontology” This review discusses the clinical aspects, diagnosis, and treatment options for androgenetic alopecia, ultimately calling for further research, particularly regarding older populations and possible health risks.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, researchers found that frontal hair follicles in individuals with androgenetic alopecia show a higher biological age compared to occipital follicles, possibly due to decreased expression of the transcriptional repressor TRPS1 in frontal dermal papillae, which may influence follicle miniaturization.
This study aimed to investigate the effects of antioxidant therapy on skin aging in MetS patients in Latvia but provides no new findings on its effectiveness.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
178 citations
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June 1994 in “Journal of Investigative Dermatology” This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.
9 citations
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February 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of tissue mechanics and extracellular matrix in skin aging processes and highlights potential therapeutic strategies, but reports no new clinical results.
January 2025 in “Stem Cells International” In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.
16 citations
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February 2010 in “Facial Plastic Surgery Clinics of North America” This article discusses the effectiveness of fat transfer for facial rejuvenation across all ethnicities, emphasizing its potential as both a primary method and a complement to traditional techniques, but reports no new clinical findings.
2 citations
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March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
1 citations
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October 1984 in “Clinics in dermatology” This article discusses the psychological impact of skin imperfections and suggests establishing a Cosmetic Dermatology Service within public health systems to address these issues ethically.
March 2026 in “Animal Models and Experimental Medicine” In a dermal Gorab knockout mouse model, this study found that Gorab mutations increase P53 protein accumulation and disrupt extracellular matrix expression, contributing to accelerated skin aging and suggesting a pathway involving epigenetic regulation.
April 2020 in “The FASEB Journal” This study found that Rap1 deficiency in mice may lead to telomere shortening, DNA damage, and impaired mitochondrial function, contributing to cardiac aging and dysfunction.
January 2016 in “Georg Thieme Verlag eBooks” The document recommends personalized, culturally sensitive treatments to rejuvenate the aging Asian face, focusing on natural results and specific techniques for skin, hair, and facial features.
April 2015 in “The FASEB Journal” This study suggests that selenium deficiency accelerates aging-related health deterioration in mice with short telomeres, providing a model for exploring selenium’s role in human aging.
187 citations
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December 2005 in “Experimental Dermatology” This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.
October 2010 in “Journal of Men's Health” This study found that adolescent men in Ireland are more likely to prefer keeping a baby over abortion in a hypothetical unplanned pregnancy, influenced by their anticipated regret and perceived familial attitudes.
September 2014 in “Springer eBooks” This review discusses how sex hormone levels and local steroid synthesis influence gender differences in aging skin, reporting no new clinical results.
August 2026 in “Women s Health” This preliminary pilot study found that a combined microneedling-assisted Panax ginseng exosome protocol with adjunctive inner gel use led to short-term improvements in patient-reported vulvovaginal symptoms and qualitative improvements in vulvar skin tone, though results are preliminary and based on a small, uncontrolled sample.
May 2004 in “Archives of Facial Plastic Surgery” This book review in the Archives of Facial Plastic Surgery discusses "Comprehensive Facial Rejuvenation: A Practical and Systematic Guide to Surgical Management of the Aging Face" but does not provide new clinical research results.
November 2024 in “Forensic Sciences” This review highlights the potential for using the Y chromosome in epigenetic analyses to better understand male-specific aging and disease mechanisms.
3 citations
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May 2011 in “Facial plastic surgery clinics of North America” This article reviews the causes and treatments of fine rhytids, highlighting the potential effectiveness of laser rejuvenation therapies but presents no new clinical results.
July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
October 2022 in “Southeast Asian journal of health professionals” This article discusses factors influencing hair greying, such as thyroid hormone levels and postmenopausal changes, and suggests lifestyle adjustments for hair health; it reports no new clinical findings.
This article reviews how environmental factors and aging contribute to skin and hair changes, including wrinkling, dryness, pigmentation changes, and hair thinning, but reports no new research findings.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This review highlights morphological factors contributing to age-related alopecia and suggests further research to understand and potentially mitigate cellular aging processes affecting hair quality.
This review discusses the role of neuroactive steroids in physiological processes and their potential involvement in neuropsychiatric disorders, but it reports no new experimental findings.
3 citations
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January 2019 in “PubMed” This article discusses the use of platelet-rich plasma in genital rejuvenation and reports no new clinical results, suggesting further research is needed to evaluate its effectiveness in this area.
February 2026 in “Journal of Aesthetic Medicine” This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.
30 citations
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August 2016 in “Skin research and technology” This study used 3D imaging to reveal age-related reductions in the volumes and connectivity of dermal papillae and rete ridges at the dermal-epidermal junction, which are not fully apparent in 2D examinations.