research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
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research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Aging Hair Follicles Rejuvenated by Transplantation to a Young Subcutaneous Environment
Old hair follicles grew better when moved to a young environment.
research Evaluation of Dry Eye and Meibomian Gland Dysfunction in Female Androgenetic Alopecia Patients
Female hair loss patients more likely to have dry eye and gland issues.
research Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling
DNA methylation changes are linked to hair growth cycles in goats.
research Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice
Low selenium levels can extend lifespan but worsen health issues.
research The Role of Nrf2 in Hearing Loss
Activating Nrf2 can help protect against hearing loss.
research Recent Omics Advances In Hair Aging Biology And Hair Biomarkers Analysis
More research is needed to understand hair aging and develop effective treatments.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research Pseudoxanthoma-Like Late-Onset Focal Dermal Elastosis
A woman had a skin condition with increased normal elastic fibers, not related to other known disorders, likely due to aging.
research Beta-Catenin-Mediated Hair Growth Induction Effect of 3,4,5-Tri-O-Caffeoylquinic Acid
3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
research Hormone Replacement Therapy and the Skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Significant Effects of Mild Endogenous Hormonal Changes in Humans: Considerations for Low-Dose Testing
Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
research Diseases of the Hair and Scalp in the Elderly
Aging can lead to poorer scalp and hair health, including less hair and more scalp diseases, which should be managed to help older people feel better.
research Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages
Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
research Changes in Androgen Levels in Menopausal Women
Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
research The Pathophysiology of Delayed Ejaculation
Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.
research The Role and Mechanism of Adipose Stem Cells in Facial Anti-Aging
Fat stem cells help rejuvenate skin, reduce wrinkles, lighten skin, and promote hair growth.
research Autologous Platelet Concentrates in Aesthetic Medicine
Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Interferon-24 Regulates the Expression of MMP1 and Dermal Collagen of the Skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research A New Scalp Treatment for Anti-Aging Hair
The new scalp treatment preserves hair color, reduces hair loss, and maintains hair strength.
research Stem Cells in Dermatology and Anti-Aging Care of the Skin
Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
research Loss of Repressor Activator Protein 1 Precipitates Cardiac Aging in Mice via p53/PPARα Signaling
Loss of Rap1 protein speeds up heart aging in mice.
research Analysis of Changes in MicroRNA Expression Profiles in Response to the Troxerutin-Mediated Antioxidant Effect in Human Dermal Papilla Cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research Anti-Aging Potential of Gypenosides Fraction Obtained from Naturally Grown Gynostemma Pentaphyllum in Ulleungdo Island and Its Seven New Gypenosides
Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.