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Plaquenil can cause a severe skin reaction called AGEP, requiring prompt diagnosis and treatment.

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

This study found that among MtF transgender individuals, those with early-onset gender dysphoria exhibited differences in age at surgery, sexual orientation, and sexual activity compared to those with later-onset dysphoria.

The study observed that in women, the number of hair follicles with an internal root sheath decreases with age in the parietal region, also hinting at a reduction in hair follicle and shaft width.

In this retrospective cohort study of individuals diagnosed with late-onset systemic lupus erythematosus after age 80, most were women, joint and skin issues were prevalent, average survival was 4.5 years, and men had notably lower survival rates with higher mortality.

This study reported that 57.4% of children under 10 with early-onset alopecia areata experienced over 50% hair regrowth after treatment with topical corticosteroids, noting that those under 4 showed significantly better responses, although personal atopic history was the only differing prognostic factor.

This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.

This case study highlights that even short-term use of hydroxychloroquine for COVID-19 can potentially lead to acute generalized exanthematous pustulosis as an adverse effect.

Avoiding certain fragrances improved the man's skin condition.

This review summarizes existing and new cases of generalized pustular psoriasis and acute generalized exanthematous pustulosis associated with COVID-19, noting that over half lacked a known drug trigger.

This case report describes a 45-year-old male with atrial fibrillation who developed acute generalized exanthematous pustulosis after starting metformin for prediabetes, highlighting a rare dermatologic reaction.

This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.

This study observed that age influences fur quality and hair follicle traits in Rex rabbits, with significant differences in the Wnt10b/β-catenin signaling pathways during hair follicle development, suggesting the ideal slaughter age should not be earlier than 120 days to maximize fur characteristics.

This study found that both Japanese male and female hair darkens with age, with significant sex differences in melanin composition and melanosome morphology influencing hair color.

This study reports that severe androgenic alopecia prevalence in young Caucasian men increases with age, varies by region, and that body mass index may be a risk factor.

This study reports that in Rex rabbits, age affects fur quality and hair follicle traits, with the Wnt signaling pathway playing a role in their periodic hair follicle development.

Eating shiitake mushrooms caused a man to develop a rash similar to a skin condition known as AGEP.

This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.

This study found that keratinocytes show increased expression of the TGF-β system and collagen type I with age, suggesting a heightened profibrotic response during skin differentiation associated with scarring.

This study found that in adults with vitiligo, certain autoimmune diseases are associated with factors like age, sex, and extent of vitiligo, suggesting tailored screening strategies based on these variables.

This study observed that estrogen receptor β and androgen receptor expressions in the skin decline with age, more noticeably under sun exposure, suggesting a role in skin aging.

This study found that among women with polycystic ovary syndrome, higher age, obesity, hirsutism, and having children were independently associated with increased metabolic risk.

This study found that the severity, duration, and relapse rate of alopecia areata decreased with older age at onset, while relapses mostly occurred early and declined over time.

This study found that patients with myotonic dystrophy type 1 had higher numbers of nevi, dysplastic nevi, melanomas, and pilomatrixomas compared to age- and sex-matched controls.

This study reports two distinct patterns of hair changes in postmenopausal women, linking diffuse generalized scalp hair loss to older age and frontal hair loss to higher facial hair scores and younger age.

This study found that patients with alopecia have limited knowledge, negative attitudes, and proactive practices toward the condition, influenced by factors such as age, COVID-19, medication, and polycystic ovary syndrome, suggesting that improving knowledge through education may enhance patient management.

In this study, physiological skin changes like linea nigra (84.4%) and striae distensae (78.4%) were most common in pregnant women, while pathological changes were shown to be significantly associated with gravida and gestational age.

In this study, researchers found that men with androgenetic alopecia had significantly higher blood levels of galectin-3 compared to healthy controls, which was associated with the progression of the disease, irrespective of age or body mass index.

This study found that most patients with chronic telogen effluvium had serum ferritin levels below hair cycle requirements, significantly linked to socioeconomic status, age, and weight factors.

In this case study, a patient developed a rash consistent with acute generalized exanthematous pustulosis after increasing the dose of semaglutide, suggesting that the reaction was likely due to the excipient propylene glycol, highlighting the importance of ingredient analysis and multidisciplinary collaboration for patient safety.