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Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Different ethnic groups have unique hair growth patterns, with African hair growing slower and less dense, Asian hair growing fast but sparse, and Caucasian hair being densest; men are more likely to experience hair loss than women.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Fullerenes show potential in skin care but need more safety research.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.