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Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

TSH is usually the only test needed to check thyroid function in primary care.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Finasteride doesn't affect sleep spindles in men.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

SIRT3 and SIRT7 genes may play a role in hair loss.

A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.

A group has developed therapies that show promise for treating cancer and various other conditions.

The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Derinat may improve hair growth and quality of life in hair loss patients by reducing oxidative stress.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

The supplement significantly improves hair density and appearance in people with hair loss.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

ADHD stimulant medications might be linked to a specific type of hair loss called Alopecia Universalis.

Finasteride affects young male rats' brain function and behavior negatively.