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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride may increase depression by reducing brain cell growth.

Four new cases of gynecomastia (male breast enlargement) linked to finasteride (Propecia) have been found.

Valproate can cause both hair loss and curly hair in bipolar disorder patients.

Long-term use of Risperidone may be linked to a serious skin condition in bipolar patients, affecting their overall well-being.

Gut flora changes could potentially indicate depression, but more research is needed.

Physical inactivity is a primary cause of many human illnesses.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

The trial aims to understand how obesity and lifestyle affect circadian rhythms in people with schizophrenia and bipolar disorder.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Hair loss from mood stabilizers can grow back, but the reasons why are not fully understood.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

The analysis found that alopecia areata, a hair loss condition, is not very common in Australia, affecting about 0.13% of people, with new cases most often seen in males aged 19 to 34 years.

University students in Egypt experienced high stress during COVID-19's third wave, with negative coping mechanisms being more common.

Crash diets can cause temporary hair loss, and professional medical advice can prevent serious health issues.

High levels of prolactin in the blood can be linked to widespread hair loss.

Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Finasteride may cause side effects; more research needed.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Women with PCOS are much more likely to experience depression.