In this review, researchers analyzed literature on trichotillomania and found advances in understanding its neurobiology—highlighting dysregulated reward circuits and genetics—and treatments, with behavioral therapy and innovative pharmacological approaches improving outcomes where traditional SSRIs do not.
May 2024 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review outlines current treatment strategies for trichotillomania, noting cognitive-behavioral therapy's success, while highlighting the promise and limitations of various pharmacological options.
September 2019 in “Journal of Investigative Dermatology” This qualitative study found that healthcare professionals view psychosocial needs as a major reason for offering therapeutic education and self-management support for psoriasis, but efficacy remains uncertain.
21 citations
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April 2015 in “Psychology Research and Behavior Management” This review evaluates various cognitive-behavioral interventions for trichotillomania but does not report new clinical findings, highlighting the need for further research on their efficacy.
3 citations
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December 2001 in “Irish Journal of Psychological Medicine” This review discusses trichotillomania, its diagnosis, prevalence, potential brain abnormalities, and current treatment options, and offers no new clinical findings.
January 2017 in “International journal of science and research” This review discusses treatment options for trichotillomania, focusing on cognitive-behavioral interventions and promising developments in combined pharmacotherapy and therapy approaches, but reports no new findings.
1 citations
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December 2023 in “Frontiers in Behavioral Neuroscience” The study found that in mice, conditional knockout of p53 in epidermal keratinocytes reduced food intake following UVB exposure and resulted in anxiety-related behaviors, suggesting that p53 plays a role in appetite stimulation and anxiety via UVB-induced β-endorphin production.
In this systematic review, researchers observed that Toxoplasma gondii infection is associated with alterations in testosterone levels, generally increasing in humans but showing mixed effects in animals, highlighting a complex relationship that warrants further investigation.
169 citations
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August 1981 in “BMJ” This study found that while sodium valproate improved seizure control in children with epilepsy, it often led to increased weight gain, with no severe side effects like liver disease or pancreatitis reported.
84 citations
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October 2005 in “Annals of Clinical Psychiatry” This review examines the existing research on pathologic hairpulling, skin picking, and nail biting, suggesting these behaviors are underrecognized and may benefit from a unified diagnostic categorization; it reports no new clinical findings.
51 citations
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May 2010 in “Journal of Drug Targeting” This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.
39 citations
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May 2015 in “Advanced drug delivery reviews” This review discusses skin tissue engineering and highlights the potential role of microRNAs in improving bioengineered skin equivalents, concluding that further exploration of microRNA targets could address unmet clinical needs.
28 citations
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December 2010 in “Langmuir” Hair fibers interact through classical forces, which are influenced by treatments and products, important for hair care and other applications.
27 citations
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September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review discusses recent advances in hair regeneration therapies, highlighting the potential of nanotechnology and pluripotent stem cells, and reports no new results, emphasizing the need for further research.
22 citations
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May 2010 in “Journal of Pediatric Gastroenterology and Nutrition” This case report documents a rare instance of Rapunzel syndrome causing biliary obstruction in a 3-year-old girl, highlighting the importance of considering trichobezoar in cholestasis diagnosis.
19 citations
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March 1999 in “PubMed” This review discusses trichotillomania, its prevalence, and treatment options, emphasizing that many sufferers experience delays in treatment due to secrecy and shame, but reports no new research findings.
13 citations
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July 2019 in “Pediatric dermatology” This review addresses dermatologic health disparities in sexual and gender minority adolescents, highlighting the need for improved pediatric dermatologic care; it does not report new clinical results.
5 citations
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January 2010 in “The anatomical record” This study assessed hair whorl characteristics in domestic dogs and found that simple whorls predominate, with tufted whorls more common in specific regions like elbows and chests, influenced by factors such as coat traits and source.
5 citations
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September 2021 in “Cureus” This paper explores the mechanisms causing depression in women with PCOS and suggests that lifestyle modifications, such as dietary changes and weight loss, as well as cognitive behavioral therapy and antidepressants, can help manage PCOS-induced depression.
2 citations
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March 2022 in “Indian Journal of Psychiatry/Indian journal of psychiatry” This article reviews the psychiatric conditions associated with HIV, highlighting the bidirectional relationship and management challenges but presents no new research findings.
1 citations
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December 2014 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.
June 2026 in “Experimental Dermatology” This review explores the roles of laminin-332 in skin function, highlighting its involvement in epidermal cohesion, stem cell maintenance, wound healing, and potential in genetic therapies for junctional epidermolysis bullosa.
March 2025 in “Scientific Reports” This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.
September 2024 in “Cureus” In this case study, a 24-year-old female with treatment-resistant trichotillomania achieved a 9-month remission of hair-pulling and hair regrowth through mindset reframing, physical barriers, and community support, suggesting these approaches may offer promising interventions for individuals with similar conditions.
October 2018 in “Annals of Reviews & Research” This open-access journal publishes innovative research articles across various fields but reports no new clinical results in this summary.
November 2004 in “Qucosa (Saxon State and University Library Dresden)” This study developed analytical methods to better understand hair treatment with cosmetic formulations, revealing that active agents primarily adsorb on the hair surface during short washes.
August 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This systematic review found that anxiety disorders are significantly more prevalent among patients with various psychodermatoses compared to the general population.
This case report chronicles a three-year journey of long COVID in a previously healthy 26-year-old, detailing treatment trials and near-total remission, but provides no new generalizable data.
January 2015 in “The Encyclopedia of Clinical Psychology” This review discusses trichotillomania treatments, highlighting that habit reversal training shows promise for children and adolescents, although further research is needed, as existing literature on this age group is sparse.
January 2012 in “Postgraduate obstetrics & gynecology” Up to 50% of women may experience significant hair loss by age 50, with various causes and treatments available.