33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” In this study, elevated afamin concentrations were associated with metabolic syndrome in young women, particularly those with insulin resistance, suggesting a potential predictive role for afamin in metabolic risk assessment.
87 citations
,
March 2013 in “Expert Review of Anticancer Therapy” This article summarizes dermatologic adverse events in patients treated with afatinib in clinical trials and discusses strategies for managing these side effects, without providing new clinical results.
6 citations
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December 2018 in “Ophthalmic Plastic and Reconstructive Surgery” This study reports a rare side effect of trichiasis in a patient with spinal chordoma treated with Afatinib, a type of epidermal growth factor receptor tyrosine kinase inhibitor.
December 2025 in “Journal of Pakistan Association of Dermatologists” This case report highlights a rare instance of erosive pustular dermatosis of the scalp in a patient on afatinib, underlining the importance of early recognition and management of this adverse effect.
58 citations
,
March 2020 in “Scientific Reports” This study mapped the safety profile of EGFR-TKIs by analyzing FDA adverse event reports, highlighting unexpected reactions like intestinal obstruction and hypokalaemia with gefitinib and erlotinib.
7 citations
,
January 2023 in “Anti-Cancer Drugs” In this study, researchers reviewed cases of EGFR inhibitor-induced folliculitis decalvans and reported the first known occurrences associated with afatinib in three female NSCLC patients, highlighting the importance of early diagnosis and management to improve patient quality of life.
June 2024 in “Journal of Clinical Oncology” This study examined the FDA Adverse Events Reporting System and found new dermatologic adverse events associated with EGFR-TKIs in non-small cell lung cancer patients, such as specific skin, nail, and hair issues, that aren't currently listed on drug labels.
January 2022 in “Social Science Research Network” This study found that most potassium channel blockers increased the activity of slowly adapting mechanoreceptors in rat whisker pads, while the opener NS1619 decreased their evoked activity.
December 2022 in “International Journal of Molecular Sciences” This study used machine learning to identify FDA-approved drugs afatinib, neratinib, and zanubrutinib as potential KRASG12C inhibitors for resistant non-small-cell lung cancer, highlighting the potential of AI in drug repurposing.
June 2021 in “Research Square (Research Square)” This study found that non-small-cell lung cancer patients experienced less adverse events with third-generation EGFR-TKIs compared to first and second generations, although fear of cancer progression, anxiety, and depression were still prevalent.
Some TikTok hair loss remedies like rosemary oil, onion juice, and garlic gel show promise, but more research is needed and they might delay proper treatment.
30 citations
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March 1980 in “European Journal of Endocrinology” This study suggests that genetic factors significantly influence adrenal androgen levels and the progression of puberty, with adrenal cortex maturation appearing independent of the hypothalamic-pituitary-gonadal axis.
15 citations
,
July 2022 in “Biomedicines” This study found that bioengineered skin substitutes developed for 21 or 28 days effectively mimic native skin's ability to absorb UV radiation, suggesting suitability for treating severe skin defects.
6 citations
,
October 2022 in “Frontiers in Oncology” This review discusses surgical approaches and new advancements in sternum reconstruction, emphasizing innovative techniques and materials, but reports no new clinical results.
5 citations
,
April 2024 in “BMC Neurology” The researchers reported that non-motor symptoms like taste disorders and alopecia are associated with myasthenia gravis, particularly in severe cases and those linked to thymoma.
This case study reports the first known instance of lichen planopilaris being associated with multiple autoimmune syndrome in a woman with hypothyroidism and Crohn's disease.
November 2022 in “SAS journal of medicine” This study found that serum ferritin levels were significantly higher in Jordanian patients with alopecia areata compared to controls, but still within the normal range.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
39 citations
,
June 2019 in “Toxins” This review explores the therapeutic potential of bee venom for treating various skin diseases, discussing its mechanisms and effects but reports no new clinical findings.
29 citations
,
September 2017 in “Oncology and therapy” This review discusses the common dermatologic side effects of epidermal growth factor receptor inhibitors and provides practical guidance for recognizing and managing these effects; it reports no new clinical results.
15 citations
,
February 2017 in “Nursing Clinics of North America” This article reviews common skin reactions associated with epidermal growth factor receptor inhibitors and reports no new clinical findings, emphasizing the need for understanding nursing care and oncodermatology.
6 citations
,
January 2024 in “ACS Medicinal Chemistry Letters” This study found that the alkaloids cepharanthine and berbamine bind to SK2 and SK3 channel subtypes with affinities that match their concentrations active against various diseases, prompting further investigation into SK channels' role in their therapeutic effects.
2 citations
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January 2018 in “Elsevier eBooks” Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study evaluated formulations of a cream containing turmeric and ginger extracts for inhibiting underarm hair growth, finding that the formulation with 15% stearic acid and 3% triethanolamine had the most optimal physical characteristics and potential for cosmetic development.
This article provides a reference guide for various dermatological terms, treatments, and conditions, but reports no new clinical findings.
December 2023 in “Research in pharmacy” This review underscores the importance of phytotherapeutic compounds and adjuncts in managing polycystic ovarian syndrome but does not present new clinical evidence.
Vitamin D is crucial for skin health and managing skin diseases.
3 citations
,
June 1983 in “Archives of Dermatology” This article discusses the effectiveness of adrenal cortex compounds E and F in treating connective tissue disorders like rheumatoid arthritis and lupus erythematosus, but it reports no new clinical results.
211 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
179 citations
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October 2018 in “American Journal of Clinical Dermatology” This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.