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This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This review discusses the differences in wound healing between fetal and adult skin, highlighting the potential to uncover genes for scarless repair that could improve adult wound healing.

This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.

This review discusses the migration and colonization of melanocytes from the neural crest in mammals and reports no new experimental results.

This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.

This review discusses current strategies and materials in tissue engineering for skin regeneration, emphasizing design approaches and suggesting directions for future research; it reports no new clinical findings.

This study observed that extracellular matrix scaffold membranes performed less effectively in wound healing for aged mice compared to younger ones, with senescent SPP1+ macrophages potentially hindering epidermal and fibroblast repair abilities.

This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

This review discusses the advances and challenges of using mesenchymal stem cell-derived extracellular vesicles in therapeutic applications and reports no new clinical findings.

This study explored the effects of TTFE on male androgenic alopecia, finding that topical application increased hair density, follicular diameter, and scalp hydration while reducing water loss and sebum production in a 12-week trial.

This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.

This review discusses potential agents, including acetyl-L-carnitine and vitamins, for repurposing in managing chemotherapy-induced peripheral neuropathy and reports no clinical results; the authors emphasize the need for further research.

This study found that Lespedeza cuneata aqueous extract reduced serum dihydrotestosterone levels and 5α-reductase mRNA expression in testosterone-induced prostatic hyperplasia in rats, suggesting potential as a treatment for prostatic hyperplasia.

This study found that PDRN derived from Lactobacillus rhamnosus showed superior antioxidant and wound-healing properties compared to salmon-derived PDRN, while also offering potential benefits in immune modulation and bioavailability.

This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.

This study reviewed clinical trials and reports on cytokine-targeting biologics for alopecia areata, finding Dupilumab and Ustekinumab showed strong efficacy, while other biologics had limited success or worsened the condition. Further research is needed to optimize biologic therapies for AA.

This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.

In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.

This review examines the clinicopathologic features of perifollicular elastolysis and indicates that, while its presentation is consistent, there is a lack of high-certainty evidence for effective treatments.

This study identified 96 cases of pilomatricomas linked to genetic syndromes, including a novel association with Apert syndrome, highlighting that these tumors often manifest as the first indication of underlying conditions in pediatric patients.

This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.

This narrative review explores the molecular mechanisms driving skin development and their role in skin diseases, emphasizing how disruptions in these pathways can lead to conditions like congenital disorders and cancers, potentially guiding new targeted therapies.

This review explores the role of transient receptor potential vanilloid channels in the pathogenesis of osteoarthritis but reports no new clinical results.

This review summarizes the research on bioactive materials that modulate the skin microenvironment to promote wound healing and highlights the essential role of the fascial layer, without presenting new experimental results.

This study found that plucked hair follicles can serve as a practical and scalable source for regenerative medicine, as researchers successfully isolated and expanded keratinocytes and mesenchymal stem cells for potential cell-based and cell-free therapies, demonstrating significant wound-healing bioactivity in vitro.

This review examines the complex role of the Ectodysplasin-A pathway in skeletal morphogenesis, emphasizing its interaction with other key signaling pathways, and reports no new experimental findings.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.