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The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

JAK inhibitors, like baricitinib, are effective and safe for treating alopecia areata.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Temporary facial blanching can occur after Botulinum toxin injections, but it resolves without discomfort.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

A woman got severe scalp burns from a salon's improper hair bleaching treatment.

Carboxytherapy can improve skin conditions with few side effects, but results may vary and are not guaranteed.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Hair loss in young men in Central India is linked to severe heart disease.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

SHBG may be a useful early indicator and treatment target for PCOS.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Veterinarians could test positive for ketamine from work exposure, not just substance abuse.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.