Search

everythinglearnresearchcommunity

for

Search:↓

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride may improve prostate cancer treatment outcomes.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Finasteride may cause kidney damage.

Possible link between androgens and COVID-19 severity; more research needed.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Trichoscopy is a useful tool for diagnosing hair and scalp diseases without needing skin biopsies.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Herpes zoster infection can cause permanent hair color change in the affected area.

Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.

Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.

Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.