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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Genetic mutations can affect female sexual development, requiring personalized medical care.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

A new gene variant causes glucocorticoid resistance in a mother and son.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The research found that MRI and certain hormone levels can help tell apart ovarian tumors from hyperthecosis in postmenopausal women, but tissue analysis is still needed for a definite diagnosis.

A postmenopausal woman's hair loss and excess hair growth improved after surgery for ovarian hyperthecosis.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.

An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.

Patterned hair loss is relatively common in women and not usually a sign of serious health issues.

A postmenopausal woman's excessive hair growth and hair loss were due to a non-cancerous ovarian condition, treated successfully with surgery.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.